Advantages and Applications of Total-Body PET Scanning

Recent studies have focused on the development of total-body PET scanning in a variety of fields such as clinical oncology, cardiology, personalized medicine, drug development and toxicology, and inflammatory/infectious disease. Given its ultrahigh detection sensitivity, enhanced temporal resolution...

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Main Authors: Sanaz Katal, Liesl S. Eibschutz, Babak Saboury, Ali Gholamrezanezhad, Abass Alavi
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/12/2/426
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author Sanaz Katal
Liesl S. Eibschutz
Babak Saboury
Ali Gholamrezanezhad
Abass Alavi
author_facet Sanaz Katal
Liesl S. Eibschutz
Babak Saboury
Ali Gholamrezanezhad
Abass Alavi
author_sort Sanaz Katal
collection DOAJ
description Recent studies have focused on the development of total-body PET scanning in a variety of fields such as clinical oncology, cardiology, personalized medicine, drug development and toxicology, and inflammatory/infectious disease. Given its ultrahigh detection sensitivity, enhanced temporal resolution, and long scan range (1940 mm), total-body PET scanning can not only image faster than traditional techniques with less administered radioactivity but also perform total-body dynamic acquisition at a longer delayed time point. These unique characteristics create several opportunities to improve image quality and can provide a deeper understanding regarding disease detection, diagnosis, staging/restaging, response to treatment, and prognostication. By reviewing the advantages of total-body PET scanning and discussing the potential clinical applications for this innovative technology, we can address specific issues encountered in routine clinical practice and ultimately improve patient care.
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spelling doaj.art-1a8cd5e1c27445f7b4788def235381822023-11-23T19:31:52ZengMDPI AGDiagnostics2075-44182022-02-0112242610.3390/diagnostics12020426Advantages and Applications of Total-Body PET ScanningSanaz Katal0Liesl S. Eibschutz1Babak Saboury2Ali Gholamrezanezhad3Abass Alavi4Independent Researcher, Melbourne 3000, AustraliaDepartment of Radiology, Keck School of Medicine, University of Southern California (USC), Los Angeles, CA 90007, USADepartment of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health (NIH), Bethesda, MD 20892, USADepartment of Radiology, Keck School of Medicine, University of Southern California (USC), Los Angeles, CA 90007, USADepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USARecent studies have focused on the development of total-body PET scanning in a variety of fields such as clinical oncology, cardiology, personalized medicine, drug development and toxicology, and inflammatory/infectious disease. Given its ultrahigh detection sensitivity, enhanced temporal resolution, and long scan range (1940 mm), total-body PET scanning can not only image faster than traditional techniques with less administered radioactivity but also perform total-body dynamic acquisition at a longer delayed time point. These unique characteristics create several opportunities to improve image quality and can provide a deeper understanding regarding disease detection, diagnosis, staging/restaging, response to treatment, and prognostication. By reviewing the advantages of total-body PET scanning and discussing the potential clinical applications for this innovative technology, we can address specific issues encountered in routine clinical practice and ultimately improve patient care.https://www.mdpi.com/2075-4418/12/2/426total-body PEToncologyFDGdrug developmentPET/CTinflammatory disease
spellingShingle Sanaz Katal
Liesl S. Eibschutz
Babak Saboury
Ali Gholamrezanezhad
Abass Alavi
Advantages and Applications of Total-Body PET Scanning
Diagnostics
total-body PET
oncology
FDG
drug development
PET/CT
inflammatory disease
title Advantages and Applications of Total-Body PET Scanning
title_full Advantages and Applications of Total-Body PET Scanning
title_fullStr Advantages and Applications of Total-Body PET Scanning
title_full_unstemmed Advantages and Applications of Total-Body PET Scanning
title_short Advantages and Applications of Total-Body PET Scanning
title_sort advantages and applications of total body pet scanning
topic total-body PET
oncology
FDG
drug development
PET/CT
inflammatory disease
url https://www.mdpi.com/2075-4418/12/2/426
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AT babaksaboury advantagesandapplicationsoftotalbodypetscanning
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AT abassalavi advantagesandapplicationsoftotalbodypetscanning