Advantages and Applications of Total-Body PET Scanning
Recent studies have focused on the development of total-body PET scanning in a variety of fields such as clinical oncology, cardiology, personalized medicine, drug development and toxicology, and inflammatory/infectious disease. Given its ultrahigh detection sensitivity, enhanced temporal resolution...
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Format: | Article |
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MDPI AG
2022-02-01
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Series: | Diagnostics |
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Online Access: | https://www.mdpi.com/2075-4418/12/2/426 |
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author | Sanaz Katal Liesl S. Eibschutz Babak Saboury Ali Gholamrezanezhad Abass Alavi |
author_facet | Sanaz Katal Liesl S. Eibschutz Babak Saboury Ali Gholamrezanezhad Abass Alavi |
author_sort | Sanaz Katal |
collection | DOAJ |
description | Recent studies have focused on the development of total-body PET scanning in a variety of fields such as clinical oncology, cardiology, personalized medicine, drug development and toxicology, and inflammatory/infectious disease. Given its ultrahigh detection sensitivity, enhanced temporal resolution, and long scan range (1940 mm), total-body PET scanning can not only image faster than traditional techniques with less administered radioactivity but also perform total-body dynamic acquisition at a longer delayed time point. These unique characteristics create several opportunities to improve image quality and can provide a deeper understanding regarding disease detection, diagnosis, staging/restaging, response to treatment, and prognostication. By reviewing the advantages of total-body PET scanning and discussing the potential clinical applications for this innovative technology, we can address specific issues encountered in routine clinical practice and ultimately improve patient care. |
first_indexed | 2024-03-09T22:11:03Z |
format | Article |
id | doaj.art-1a8cd5e1c27445f7b4788def23538182 |
institution | Directory Open Access Journal |
issn | 2075-4418 |
language | English |
last_indexed | 2024-03-09T22:11:03Z |
publishDate | 2022-02-01 |
publisher | MDPI AG |
record_format | Article |
series | Diagnostics |
spelling | doaj.art-1a8cd5e1c27445f7b4788def235381822023-11-23T19:31:52ZengMDPI AGDiagnostics2075-44182022-02-0112242610.3390/diagnostics12020426Advantages and Applications of Total-Body PET ScanningSanaz Katal0Liesl S. Eibschutz1Babak Saboury2Ali Gholamrezanezhad3Abass Alavi4Independent Researcher, Melbourne 3000, AustraliaDepartment of Radiology, Keck School of Medicine, University of Southern California (USC), Los Angeles, CA 90007, USADepartment of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health (NIH), Bethesda, MD 20892, USADepartment of Radiology, Keck School of Medicine, University of Southern California (USC), Los Angeles, CA 90007, USADepartment of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USARecent studies have focused on the development of total-body PET scanning in a variety of fields such as clinical oncology, cardiology, personalized medicine, drug development and toxicology, and inflammatory/infectious disease. Given its ultrahigh detection sensitivity, enhanced temporal resolution, and long scan range (1940 mm), total-body PET scanning can not only image faster than traditional techniques with less administered radioactivity but also perform total-body dynamic acquisition at a longer delayed time point. These unique characteristics create several opportunities to improve image quality and can provide a deeper understanding regarding disease detection, diagnosis, staging/restaging, response to treatment, and prognostication. By reviewing the advantages of total-body PET scanning and discussing the potential clinical applications for this innovative technology, we can address specific issues encountered in routine clinical practice and ultimately improve patient care.https://www.mdpi.com/2075-4418/12/2/426total-body PEToncologyFDGdrug developmentPET/CTinflammatory disease |
spellingShingle | Sanaz Katal Liesl S. Eibschutz Babak Saboury Ali Gholamrezanezhad Abass Alavi Advantages and Applications of Total-Body PET Scanning Diagnostics total-body PET oncology FDG drug development PET/CT inflammatory disease |
title | Advantages and Applications of Total-Body PET Scanning |
title_full | Advantages and Applications of Total-Body PET Scanning |
title_fullStr | Advantages and Applications of Total-Body PET Scanning |
title_full_unstemmed | Advantages and Applications of Total-Body PET Scanning |
title_short | Advantages and Applications of Total-Body PET Scanning |
title_sort | advantages and applications of total body pet scanning |
topic | total-body PET oncology FDG drug development PET/CT inflammatory disease |
url | https://www.mdpi.com/2075-4418/12/2/426 |
work_keys_str_mv | AT sanazkatal advantagesandapplicationsoftotalbodypetscanning AT lieslseibschutz advantagesandapplicationsoftotalbodypetscanning AT babaksaboury advantagesandapplicationsoftotalbodypetscanning AT aligholamrezanezhad advantagesandapplicationsoftotalbodypetscanning AT abassalavi advantagesandapplicationsoftotalbodypetscanning |