The impact of tumor metabolic activity assessed by 18F-FET amino acid PET imaging in particle radiotherapy of high-grade glioma patients

The impact of tumor metabolic activity assessed by 18F-FET amino acid PET imaging in particle radiotherapy of high-grade glioma patients

BackgroundSelective uptake of (18)F-fluoro-ethyl-tyrosine (18F-FET) is used in high-grade glioma (HGG) to assess tumor metabolic activity via positron emission tomography (PET). We aim to investigate its value for target volume definition, as a prognosticator, and associations with whole-blood trans...

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Bibliographic Details
Main Authors: Maria Waltenberger, Jennifer Furkel, Manuel Röhrich, Patrick Salome, Charlotte Debus, Bouchra Tawk, Aoife Ward Gahlawat, Andreas Kudak, Matthias Dostal, Ute Wirkner, Christian Schwager, Christel Herold-Mende, Stephanie E. Combs, Laila König, Jürgen Debus, Uwe Haberkorn, Amir Abdollahi, Maximilian Knoll
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
particle therapy
18F-FET-PET
liquid biopsy
whole blood transcriptome
conformity index (CI)
high grade glioma (HGG)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.901390/full

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