Review: Optimal use of biologics in the management of Crohn’s disease

Crohn’s disease (CD) is a chronic relapsing and remitting disorder of the gastrointestinal tract with no known cure. The inflammation that drives the disease can lead to debilitating symptoms and a number of complications that may lead to surgery. The introduction of biologic therapy a decade ago ha...

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Main Authors: Remo Panaccione MD, FRCPC, Subrata Ghosh MD, FRCP, FRCP(E)
Format: Article
Language:English
Published: SAGE Publishing 2010-05-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756283X09357579
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author Remo Panaccione MD, FRCPC
Subrata Ghosh MD, FRCP, FRCP(E)
author_facet Remo Panaccione MD, FRCPC
Subrata Ghosh MD, FRCP, FRCP(E)
author_sort Remo Panaccione MD, FRCPC
collection DOAJ
description Crohn’s disease (CD) is a chronic relapsing and remitting disorder of the gastrointestinal tract with no known cure. The inflammation that drives the disease can lead to debilitating symptoms and a number of complications that may lead to surgery. The introduction of biologic therapy a decade ago has offered a new option for patients failing conventional therapy. Over time, biologic therapy has also led to the desire to achieve treatment goals beyond the control of symptoms. In order to achieve short-term and long-term goals with these new agents, it is important to review how these therapies may be optimized for the best results.
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spelling doaj.art-1a9720bc55674d969df192aaf62d239c2022-12-21T19:51:16ZengSAGE PublishingTherapeutic Advances in Gastroenterology1756-283X2010-05-01310.1177/1756283X09357579Review: Optimal use of biologics in the management of Crohn’s diseaseRemo Panaccione MD, FRCPCSubrata Ghosh MD, FRCP, FRCP(E)Crohn’s disease (CD) is a chronic relapsing and remitting disorder of the gastrointestinal tract with no known cure. The inflammation that drives the disease can lead to debilitating symptoms and a number of complications that may lead to surgery. The introduction of biologic therapy a decade ago has offered a new option for patients failing conventional therapy. Over time, biologic therapy has also led to the desire to achieve treatment goals beyond the control of symptoms. In order to achieve short-term and long-term goals with these new agents, it is important to review how these therapies may be optimized for the best results.https://doi.org/10.1177/1756283X09357579
spellingShingle Remo Panaccione MD, FRCPC
Subrata Ghosh MD, FRCP, FRCP(E)
Review: Optimal use of biologics in the management of Crohn’s disease
Therapeutic Advances in Gastroenterology
title Review: Optimal use of biologics in the management of Crohn’s disease
title_full Review: Optimal use of biologics in the management of Crohn’s disease
title_fullStr Review: Optimal use of biologics in the management of Crohn’s disease
title_full_unstemmed Review: Optimal use of biologics in the management of Crohn’s disease
title_short Review: Optimal use of biologics in the management of Crohn’s disease
title_sort review optimal use of biologics in the management of crohn s disease
url https://doi.org/10.1177/1756283X09357579
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