Preoperative serum calcium could be a prognostic factor for surgical treatment of recurrent patellar dislocation: a retrospective study
Abstract Background Surgical treatment for recurrent patellar dislocation (RPD) could yield good outcomes. While, unsatisfactory recovery still exists in some cases. For all prognostic factors, serum biomarkers have rarely been investigated. This study aimed to evaluate the prognostic value of preop...
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| Format: | Article |
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BMC
2022-06-01
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| Series: | BMC Musculoskeletal Disorders |
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| Online Access: | https://doi.org/10.1186/s12891-022-05527-y |
| _version_ | 1818205283497803776 |
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| author | Yi Qiao Zipeng Ye Junjie Xu Xiuyuan Zhang Jiebo Chen Caiqi Xu Song Zhao Jinzhong Zhao |
| author_facet | Yi Qiao Zipeng Ye Junjie Xu Xiuyuan Zhang Jiebo Chen Caiqi Xu Song Zhao Jinzhong Zhao |
| author_sort | Yi Qiao |
| collection | DOAJ |
| description | Abstract Background Surgical treatment for recurrent patellar dislocation (RPD) could yield good outcomes. While, unsatisfactory recovery still exists in some cases. For all prognostic factors, serum biomarkers have rarely been investigated. This study aimed to evaluate the prognostic value of preoperative serum calcium level, a widely used serum biomarker, in surgical treatment for RPD. Study design Retrospective study. Methods Ninety-nine patients with RPD were enrolled in the study. Preoperative serum calcium was acquired from routinely tested blood 1 day prior to operation. Demographic data, characteristics of RPD, postoperative functional outcomes were obtained. The association between preoperative calcium and postoperative functional outcomes (Kujala, Lysholm, Tegner, IKDC and KOOS score) was determined by correlation analysis and multivariate linear regression analysis. Poor recovery was determined as Kujala score below 80. The receiver operating characteristic (ROC) curve was used to assess the prognostic value of preoperative calcium. Results Patients were followed up for a mean period of 2.45 ± 1.33 years. All clinical scores showed significant improvement at the latest follow-up. Correlation and multivariate linear analyses indicated that serum calcium level was an important factor related with the prognosis of surgical treatment for RPD. According to the ROC curve, the cut-off value for preoperative calcium was 2.225 mmol/L. The clinical outcomes of patients with a preoperative blood calcium < 2.225 mmol/L was significantly worse than that with a higher calcium level. The correspondent sensitivity was 0.812 with a specificity of 0.633. Conclusion Operative treatment for RPD achieved good results, while in some cases the functional scores remain inferior. As a serum biomarker, preoperative calcium could be prognostic for outcomes after surgical treatment for RPD. |
| first_indexed | 2024-12-12T03:54:40Z |
| format | Article |
| id | doaj.art-1a98aa2d57464439aba981778e34890b |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-12-12T03:54:40Z |
| publishDate | 2022-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-1a98aa2d57464439aba981778e34890b2022-12-22T00:39:17ZengBMCBMC Musculoskeletal Disorders1471-24742022-06-012311810.1186/s12891-022-05527-yPreoperative serum calcium could be a prognostic factor for surgical treatment of recurrent patellar dislocation: a retrospective studyYi Qiao0Zipeng Ye1Junjie Xu2Xiuyuan Zhang3Jiebo Chen4Caiqi Xu5Song Zhao6Jinzhong Zhao7Department of Sports Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s HospitalDepartment of Sports Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s HospitalDepartment of Sports Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s HospitalDepartment of Sports Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s HospitalDepartment of Sports Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s HospitalDepartment of Sports Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s HospitalDepartment of Sports Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s HospitalDepartment of Sports Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s HospitalAbstract Background Surgical treatment for recurrent patellar dislocation (RPD) could yield good outcomes. While, unsatisfactory recovery still exists in some cases. For all prognostic factors, serum biomarkers have rarely been investigated. This study aimed to evaluate the prognostic value of preoperative serum calcium level, a widely used serum biomarker, in surgical treatment for RPD. Study design Retrospective study. Methods Ninety-nine patients with RPD were enrolled in the study. Preoperative serum calcium was acquired from routinely tested blood 1 day prior to operation. Demographic data, characteristics of RPD, postoperative functional outcomes were obtained. The association between preoperative calcium and postoperative functional outcomes (Kujala, Lysholm, Tegner, IKDC and KOOS score) was determined by correlation analysis and multivariate linear regression analysis. Poor recovery was determined as Kujala score below 80. The receiver operating characteristic (ROC) curve was used to assess the prognostic value of preoperative calcium. Results Patients were followed up for a mean period of 2.45 ± 1.33 years. All clinical scores showed significant improvement at the latest follow-up. Correlation and multivariate linear analyses indicated that serum calcium level was an important factor related with the prognosis of surgical treatment for RPD. According to the ROC curve, the cut-off value for preoperative calcium was 2.225 mmol/L. The clinical outcomes of patients with a preoperative blood calcium < 2.225 mmol/L was significantly worse than that with a higher calcium level. The correspondent sensitivity was 0.812 with a specificity of 0.633. Conclusion Operative treatment for RPD achieved good results, while in some cases the functional scores remain inferior. As a serum biomarker, preoperative calcium could be prognostic for outcomes after surgical treatment for RPD.https://doi.org/10.1186/s12891-022-05527-yRecurrent patellar dislocationPrognosisCalciumSerum biomarker |
| spellingShingle | Yi Qiao Zipeng Ye Junjie Xu Xiuyuan Zhang Jiebo Chen Caiqi Xu Song Zhao Jinzhong Zhao Preoperative serum calcium could be a prognostic factor for surgical treatment of recurrent patellar dislocation: a retrospective study BMC Musculoskeletal Disorders Recurrent patellar dislocation Prognosis Calcium Serum biomarker |
| title | Preoperative serum calcium could be a prognostic factor for surgical treatment of recurrent patellar dislocation: a retrospective study |
| title_full | Preoperative serum calcium could be a prognostic factor for surgical treatment of recurrent patellar dislocation: a retrospective study |
| title_fullStr | Preoperative serum calcium could be a prognostic factor for surgical treatment of recurrent patellar dislocation: a retrospective study |
| title_full_unstemmed | Preoperative serum calcium could be a prognostic factor for surgical treatment of recurrent patellar dislocation: a retrospective study |
| title_short | Preoperative serum calcium could be a prognostic factor for surgical treatment of recurrent patellar dislocation: a retrospective study |
| title_sort | preoperative serum calcium could be a prognostic factor for surgical treatment of recurrent patellar dislocation a retrospective study |
| topic | Recurrent patellar dislocation Prognosis Calcium Serum biomarker |
| url | https://doi.org/10.1186/s12891-022-05527-y |
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