A comprehensive search for recombinogenic motifs in the human genome.
The patterns of male and female recombination vary greatly on a macro scale. A unique motif in each gender, triggering a double strand break at its location, much in the way Chi sites operate in E. coli, could logically explain this difference. As such, we have undertaken a comprehensive search of a...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3633838?pdf=render |
| _version_ | 1818179795497779200 |
|---|---|
| author | Henry R Johnston David J Cutler |
| author_facet | Henry R Johnston David J Cutler |
| author_sort | Henry R Johnston |
| collection | DOAJ |
| description | The patterns of male and female recombination vary greatly on a macro scale. A unique motif in each gender, triggering a double strand break at its location, much in the way Chi sites operate in E. coli, could logically explain this difference. As such, we have undertaken a comprehensive search of all small motifs in an attempt to identify one or more that match to the available data. In the end, we conclude that no such motifs appear to exist in the human genome. |
| first_indexed | 2024-12-11T21:09:33Z |
| format | Article |
| id | doaj.art-1a992a42403f4356ba2c6faac459983f |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-11T21:09:33Z |
| publishDate | 2013-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-1a992a42403f4356ba2c6faac459983f2022-12-22T00:50:46ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-0184e6292010.1371/journal.pone.0062920A comprehensive search for recombinogenic motifs in the human genome.Henry R JohnstonDavid J CutlerThe patterns of male and female recombination vary greatly on a macro scale. A unique motif in each gender, triggering a double strand break at its location, much in the way Chi sites operate in E. coli, could logically explain this difference. As such, we have undertaken a comprehensive search of all small motifs in an attempt to identify one or more that match to the available data. In the end, we conclude that no such motifs appear to exist in the human genome.http://europepmc.org/articles/PMC3633838?pdf=render |
| spellingShingle | Henry R Johnston David J Cutler A comprehensive search for recombinogenic motifs in the human genome. PLoS ONE |
| title | A comprehensive search for recombinogenic motifs in the human genome. |
| title_full | A comprehensive search for recombinogenic motifs in the human genome. |
| title_fullStr | A comprehensive search for recombinogenic motifs in the human genome. |
| title_full_unstemmed | A comprehensive search for recombinogenic motifs in the human genome. |
| title_short | A comprehensive search for recombinogenic motifs in the human genome. |
| title_sort | comprehensive search for recombinogenic motifs in the human genome |
| url | http://europepmc.org/articles/PMC3633838?pdf=render |
| work_keys_str_mv | AT henryrjohnston acomprehensivesearchforrecombinogenicmotifsinthehumangenome AT davidjcutler acomprehensivesearchforrecombinogenicmotifsinthehumangenome AT henryrjohnston comprehensivesearchforrecombinogenicmotifsinthehumangenome AT davidjcutler comprehensivesearchforrecombinogenicmotifsinthehumangenome |