The psychiatric risk gene BRD1 modulates mitochondrial bioenergetics by transcriptional regulation

The psychiatric risk gene BRD1 modulates mitochondrial bioenergetics by transcriptional regulation

Abstract Bromodomain containing 1 (BRD1) encodes an epigenetic regulator that controls the expression of genetic networks linked to mental illness. BRD1 is essential for normal brain development and its role in psychopathology has been demonstrated in genetic and preclinical studies. However, the ne...

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Main Authors: Veerle Paternoster, Cagla Cömert, Louise Sand Kirk, Sanne Hage la Cour, Tue Fryland, Paula Fernandez-Guerra, Magnus Stougaard, Jens Randel Nyengaard, Per Qvist, Peter Bross, Anders Dupont Børglum, Jane Hvarregaard Christensen
Format: Article
Language:English
Published: Nature Publishing Group 2022-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-02053-2

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