A predictive computational platform for optimizing the design of bioartificial pancreas devices
Transplanting encapsulated insulin-producing cells may achieve a functional cure for type 1 diabetes, but efficacy is constrained by mass transfer limits. Here, the authors report a dynamic computational platform to investigate the therapeutic potency of such programmable bioartificial pancreas devi...
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Bibliographic Details
| Main Authors: |
Alexander U. Ernst,
Long-Hai Wang,
Scott C. Worland,
Braulio A. Marfil-Garza,
Xi Wang,
Wanjun Liu,
Alan Chiu,
Tatsuya Kin,
Doug O’Gorman,
Scott Steinschneider,
Ashim K. Datta,
Klearchos K. Papas,
A. M. James Shapiro,
Minglin Ma |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-10-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-022-33760-5
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