A green protocol for the synthesis of quinoxaline derivatives catalyzed by polymer supported sulphanilic acid
Polymer supported sulphanilic acid was found to be an effective heterogeneous catalyst for one pot synthesis of various quinoxaline derivatives from the condensation reaction between 1,2-diamines and 1,2-dicarbonyl compounds in ethanol. Synthesis was attempted under reflux as well as at room tempera...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2017-05-01
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| Series: | Arabian Journal of Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535213003912 |
| _version_ | 1818341112387993600 |
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| author | Umesh P. Tarpada Bhautik B. Thummar Dipak K. Raval |
| author_facet | Umesh P. Tarpada Bhautik B. Thummar Dipak K. Raval |
| author_sort | Umesh P. Tarpada |
| collection | DOAJ |
| description | Polymer supported sulphanilic acid was found to be an effective heterogeneous catalyst for one pot synthesis of various quinoxaline derivatives from the condensation reaction between 1,2-diamines and 1,2-dicarbonyl compounds in ethanol. Synthesis was attempted under reflux as well as at room temperature using ethanol as the solvent to afford excellent yields. Heterogeneity of the catalyst allowed its recycling for five times with almost retention in catalytic activity. Prepared quinoxaline derivatives were also tested for their antioxidant activity by the FRAP assay method. |
| first_indexed | 2024-12-13T15:53:37Z |
| format | Article |
| id | doaj.art-1a9d8a033af44bc2af44b0c635c2236a |
| institution | Directory Open Access Journal |
| issn | 1878-5352 |
| language | English |
| last_indexed | 2024-12-13T15:53:37Z |
| publishDate | 2017-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Arabian Journal of Chemistry |
| spelling | doaj.art-1a9d8a033af44bc2af44b0c635c2236a2022-12-21T23:39:23ZengElsevierArabian Journal of Chemistry1878-53522017-05-0110S2S2902S290710.1016/j.arabjc.2013.11.021A green protocol for the synthesis of quinoxaline derivatives catalyzed by polymer supported sulphanilic acidUmesh P. TarpadaBhautik B. ThummarDipak K. RavalPolymer supported sulphanilic acid was found to be an effective heterogeneous catalyst for one pot synthesis of various quinoxaline derivatives from the condensation reaction between 1,2-diamines and 1,2-dicarbonyl compounds in ethanol. Synthesis was attempted under reflux as well as at room temperature using ethanol as the solvent to afford excellent yields. Heterogeneity of the catalyst allowed its recycling for five times with almost retention in catalytic activity. Prepared quinoxaline derivatives were also tested for their antioxidant activity by the FRAP assay method.http://www.sciencedirect.com/science/article/pii/S1878535213003912QuinoxalineAntioxidant activityHeterogeneous catalystPhenylenediamine1,2-Diarylketone |
| spellingShingle | Umesh P. Tarpada Bhautik B. Thummar Dipak K. Raval A green protocol for the synthesis of quinoxaline derivatives catalyzed by polymer supported sulphanilic acid Arabian Journal of Chemistry Quinoxaline Antioxidant activity Heterogeneous catalyst Phenylenediamine 1,2-Diarylketone |
| title | A green protocol for the synthesis of quinoxaline derivatives catalyzed by polymer supported sulphanilic acid |
| title_full | A green protocol for the synthesis of quinoxaline derivatives catalyzed by polymer supported sulphanilic acid |
| title_fullStr | A green protocol for the synthesis of quinoxaline derivatives catalyzed by polymer supported sulphanilic acid |
| title_full_unstemmed | A green protocol for the synthesis of quinoxaline derivatives catalyzed by polymer supported sulphanilic acid |
| title_short | A green protocol for the synthesis of quinoxaline derivatives catalyzed by polymer supported sulphanilic acid |
| title_sort | green protocol for the synthesis of quinoxaline derivatives catalyzed by polymer supported sulphanilic acid |
| topic | Quinoxaline Antioxidant activity Heterogeneous catalyst Phenylenediamine 1,2-Diarylketone |
| url | http://www.sciencedirect.com/science/article/pii/S1878535213003912 |
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