Dual radioisotopes simultaneous SPECT of 99mTc-tetrofosmin and 123I-BMIPP using a semiconductor detector.
Objective(s): The energy resolution of a cadmium-zinc-telluride (CZT) solid-state semiconductor detector is about 5%, and is superior to the resolution of the conventional Anger type detector which is 10%. Also, the window width of the high-energy part and of the low-energy part of a photo peak wind...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2015-01-01
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| Series: | Asia Oceania Journal of Nuclear Medicine and Biology |
| Subjects: | |
| Online Access: | http://aojnmb.mums.ac.ir/pdf_3081_486a8cfe36357e9962c6d1373940f102.html |
| _version_ | 1819229171288637440 |
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| author | Yasuyuki Takahashi Masao Miyagawa Yoshiko Nishiyama Naoto Kawaguchi Hayato Ishimura Teruhito Mochizuki |
| author_facet | Yasuyuki Takahashi Masao Miyagawa Yoshiko Nishiyama Naoto Kawaguchi Hayato Ishimura Teruhito Mochizuki |
| author_sort | Yasuyuki Takahashi |
| collection | DOAJ |
| description | Objective(s): The energy resolution of a cadmium-zinc-telluride (CZT) solid-state
semiconductor detector is about 5%, and is superior to the resolution of the conventional
Anger type detector which is 10%. Also, the window width of the high-energy part and of the
low-energy part of a photo peak window can be changed separately. In this study, we used a
semiconductor detector and examined the effects of changing energy window widths for 99mTc
and 123 I simultaneous SPECT.
Methods: The energy “centerline” for 99mTc was set at 140.5 keV and that for 123I at 159.0 keV.
For 99mTc, the “low-energy-window width” was set to values that varied from 3% to 10% of
140.5 keV and the “high-energy-window width” were independently set to values that varied
from 3% to 6% of 140.5 keV. For 123I, the “low energy-window-width” varied from 3% to 6%
of 159.0 keV and the high-energy-window width from 3% to 10% of 159 keV. In this study
we imaged the cardiac phantom, using single or dual radionuclide, changing energy window
width, and comparing SPECT counts as well as crosstalk ratio.
Results: The contamination to the 123I window from 99mTc (the crosstalk) was only 1% or
less with cutoffs of 4% at lower part and 6% at upper part of 159KeV. On the other hand,
the crosstalk from 123I photons into the 99mTc window mostly exceeded 20%. Therefore, in
order to suppress the rate of contamination to 20% or less, 99mTc window cutoffs were set at
3% in upper part and 7% at lower part of 140.5 KeV. The semiconductor detector improves
separation accuracy of the acquisition inherently at dual radionuclide imaging. In, this
phantom study we simulated dual radionuclide simultaneous SPECT by 99mTc-tetrofosmin
and 123 I-BMIPP.
Conclusion: We suggest that dual radionuclide simultaneous SPECT of 99mTc and 123I using a
CZT semiconductor detector is possible employing the recommended windows. |
| first_indexed | 2024-12-23T11:08:53Z |
| format | Article |
| id | doaj.art-1aa429f1b3a1493c82f301bc6ad78793 |
| institution | Directory Open Access Journal |
| issn | 2322-5718 2322-5726 |
| language | English |
| last_indexed | 2024-12-23T11:08:53Z |
| publishDate | 2015-01-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Asia Oceania Journal of Nuclear Medicine and Biology |
| spelling | doaj.art-1aa429f1b3a1493c82f301bc6ad787932022-12-21T17:49:24ZengMashhad University of Medical SciencesAsia Oceania Journal of Nuclear Medicine and Biology2322-57182322-57262015-01-013143493081Dual radioisotopes simultaneous SPECT of 99mTc-tetrofosmin and 123I-BMIPP using a semiconductor detector.Yasuyuki Takahashi0Masao Miyagawa1Yoshiko Nishiyama2Naoto Kawaguchi3Hayato Ishimura4Teruhito Mochizuki5Department of Nuclear Medicine Technology, Gunma Prefectural College of Health SciencesDepartment of Radiology, Ehime University Graduate School of MedicineDepartment of Radiology, Ehime University Graduate School of MedicineDepartment of Radiology, Ehime University Graduate School of MedicineDepartment of Radiological Technology, Ehime University HospitalDepartment of Radiology, Ehime University Graduate School of MedicineObjective(s): The energy resolution of a cadmium-zinc-telluride (CZT) solid-state semiconductor detector is about 5%, and is superior to the resolution of the conventional Anger type detector which is 10%. Also, the window width of the high-energy part and of the low-energy part of a photo peak window can be changed separately. In this study, we used a semiconductor detector and examined the effects of changing energy window widths for 99mTc and 123 I simultaneous SPECT. Methods: The energy “centerline” for 99mTc was set at 140.5 keV and that for 123I at 159.0 keV. For 99mTc, the “low-energy-window width” was set to values that varied from 3% to 10% of 140.5 keV and the “high-energy-window width” were independently set to values that varied from 3% to 6% of 140.5 keV. For 123I, the “low energy-window-width” varied from 3% to 6% of 159.0 keV and the high-energy-window width from 3% to 10% of 159 keV. In this study we imaged the cardiac phantom, using single or dual radionuclide, changing energy window width, and comparing SPECT counts as well as crosstalk ratio. Results: The contamination to the 123I window from 99mTc (the crosstalk) was only 1% or less with cutoffs of 4% at lower part and 6% at upper part of 159KeV. On the other hand, the crosstalk from 123I photons into the 99mTc window mostly exceeded 20%. Therefore, in order to suppress the rate of contamination to 20% or less, 99mTc window cutoffs were set at 3% in upper part and 7% at lower part of 140.5 KeV. The semiconductor detector improves separation accuracy of the acquisition inherently at dual radionuclide imaging. In, this phantom study we simulated dual radionuclide simultaneous SPECT by 99mTc-tetrofosmin and 123 I-BMIPP. Conclusion: We suggest that dual radionuclide simultaneous SPECT of 99mTc and 123I using a CZT semiconductor detector is possible employing the recommended windows.http://aojnmb.mums.ac.ir/pdf_3081_486a8cfe36357e9962c6d1373940f102.htmlSemiconductor detectorEnergy resolutionDual radioisotopes simultaneous SPECT123I-BMIPP |
| spellingShingle | Yasuyuki Takahashi Masao Miyagawa Yoshiko Nishiyama Naoto Kawaguchi Hayato Ishimura Teruhito Mochizuki Dual radioisotopes simultaneous SPECT of 99mTc-tetrofosmin and 123I-BMIPP using a semiconductor detector. Asia Oceania Journal of Nuclear Medicine and Biology Semiconductor detector Energy resolution Dual radioisotopes simultaneous SPECT 123I-BMIPP |
| title | Dual radioisotopes simultaneous SPECT of 99mTc-tetrofosmin and 123I-BMIPP using a semiconductor detector. |
| title_full | Dual radioisotopes simultaneous SPECT of 99mTc-tetrofosmin and 123I-BMIPP using a semiconductor detector. |
| title_fullStr | Dual radioisotopes simultaneous SPECT of 99mTc-tetrofosmin and 123I-BMIPP using a semiconductor detector. |
| title_full_unstemmed | Dual radioisotopes simultaneous SPECT of 99mTc-tetrofosmin and 123I-BMIPP using a semiconductor detector. |
| title_short | Dual radioisotopes simultaneous SPECT of 99mTc-tetrofosmin and 123I-BMIPP using a semiconductor detector. |
| title_sort | dual radioisotopes simultaneous spect of 99mtc tetrofosmin and 123i bmipp using a semiconductor detector |
| topic | Semiconductor detector Energy resolution Dual radioisotopes simultaneous SPECT 123I-BMIPP |
| url | http://aojnmb.mums.ac.ir/pdf_3081_486a8cfe36357e9962c6d1373940f102.html |
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