Correlation of the tumor escape phenotype with loss of PRELP expression in melanoma

Correlation of the tumor escape phenotype with loss of PRELP expression in melanoma

Abstract Background Despite immunotherapies having revolutionized the treatment of advanced cutaneous melanoma, effective and durable responses were only reported in a few patients. A better understanding of the interaction of melanoma cells with the microenvironment, including extracellular matrix...

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Bibliographic Details
Main Authors: Helene Schäfer, Karthikeyan Subbarayan, Chiara Massa, Christoforos Vaxevanis, Anja Mueller, Barbara Seliger
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Translational Medicine
Subjects:
PRELP
Melanoma
MHC class I
Antigen processing
Immunogenicity
IFN signaling
Online Access:https://doi.org/10.1186/s12967-023-04476-x

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