Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil
<p>Abstract</p> <p>Background</p> <p>Porcine circovirus type 2 (PCV2) has been associated with several disease complexes, including reproductive failure. The aim of this study was to identify the subtypes of PCV2 that are associated with reproductive failure in pigs fro...
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| Format: | Article |
| Language: | English |
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BMC
2012-05-01
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| Series: | Acta Veterinaria Scandinavica |
| Subjects: | |
| Online Access: | http://www.actavetscand.com/content/54/1/29 |
| _version_ | 1828268166938099712 |
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| author | de Castro Alessandra MMG Cruz Taís F Salgado Vanessa R Kanashiro Tatiana M Ferrari Karen L Araujo João P Brandão Paulo E Richtzenhain Leonardo J |
| author_facet | de Castro Alessandra MMG Cruz Taís F Salgado Vanessa R Kanashiro Tatiana M Ferrari Karen L Araujo João P Brandão Paulo E Richtzenhain Leonardo J |
| author_sort | de Castro Alessandra MMG |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Porcine circovirus type 2 (PCV2) has been associated with several disease complexes, including reproductive failure. The aim of this study was to identify the subtypes of PCV2 that are associated with reproductive failure in pigs from the State of São Paulo, Brazil and to investigate co-infections with other infectious organisms.</p> <p>Findings</p> <p>Samples of 168 aborted foetuses or mummified foetuses from five farrow-to-finish swine farms known to be infected with PCV2 and located in the State of São Paulo were tested for PCV2 by polymerase chain reaction (PCR). Positive samples were additionally tested for porcine parvovirus (PPV), <it>Leptospira</it> spp. and <it>Brucella</it> spp. by PCR. PCV2 was detected in 18 of the samples (10.7%). PPV, <it>Brucella</it> spp. and <it>Leptospira</it> spp were found in 2, 10 and 0 cases, respectively. Eleven PCV2 strains were sequenced and determined to be either genotype 2a (n = 1) or 2b (n = 10).</p> <p>Conclusions</p> <p>The findings indicate that the frequency of PCV2 infections in aborted porcine foetuses from the State of São Paulo is rather low (10.7%) and that co-infection with other pathogens is common and may be involved in PCV2 associated reproductive failure. No repeatable, characteristic amino acid motifs for regions of the PCV2 capsid protein seemed to be associated with abortion in sows.</p> |
| first_indexed | 2024-04-13T05:15:23Z |
| format | Article |
| id | doaj.art-1aa5d0885df94529b49aa8e9f3b6e21d |
| institution | Directory Open Access Journal |
| issn | 1751-0147 |
| language | English |
| last_indexed | 2024-04-13T05:15:23Z |
| publishDate | 2012-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Acta Veterinaria Scandinavica |
| spelling | doaj.art-1aa5d0885df94529b49aa8e9f3b6e21d2022-12-22T03:00:55ZengBMCActa Veterinaria Scandinavica1751-01472012-05-015412910.1186/1751-0147-54-29Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazilde Castro Alessandra MMGCruz Taís FSalgado Vanessa RKanashiro Tatiana MFerrari Karen LAraujo João PBrandão Paulo ERichtzenhain Leonardo J<p>Abstract</p> <p>Background</p> <p>Porcine circovirus type 2 (PCV2) has been associated with several disease complexes, including reproductive failure. The aim of this study was to identify the subtypes of PCV2 that are associated with reproductive failure in pigs from the State of São Paulo, Brazil and to investigate co-infections with other infectious organisms.</p> <p>Findings</p> <p>Samples of 168 aborted foetuses or mummified foetuses from five farrow-to-finish swine farms known to be infected with PCV2 and located in the State of São Paulo were tested for PCV2 by polymerase chain reaction (PCR). Positive samples were additionally tested for porcine parvovirus (PPV), <it>Leptospira</it> spp. and <it>Brucella</it> spp. by PCR. PCV2 was detected in 18 of the samples (10.7%). PPV, <it>Brucella</it> spp. and <it>Leptospira</it> spp were found in 2, 10 and 0 cases, respectively. Eleven PCV2 strains were sequenced and determined to be either genotype 2a (n = 1) or 2b (n = 10).</p> <p>Conclusions</p> <p>The findings indicate that the frequency of PCV2 infections in aborted porcine foetuses from the State of São Paulo is rather low (10.7%) and that co-infection with other pathogens is common and may be involved in PCV2 associated reproductive failure. No repeatable, characteristic amino acid motifs for regions of the PCV2 capsid protein seemed to be associated with abortion in sows.</p>http://www.actavetscand.com/content/54/1/29PigAbortionPorcine circovirusPorcine parvovirus<it>Brucella</it> |
| spellingShingle | de Castro Alessandra MMG Cruz Taís F Salgado Vanessa R Kanashiro Tatiana M Ferrari Karen L Araujo João P Brandão Paulo E Richtzenhain Leonardo J Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil Acta Veterinaria Scandinavica Pig Abortion Porcine circovirus Porcine parvovirus <it>Brucella</it> |
| title | Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil |
| title_full | Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil |
| title_fullStr | Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil |
| title_full_unstemmed | Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil |
| title_short | Detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the State of São Paulo, Brazil |
| title_sort | detection of porcine circovirus genotypes 2a and 2b in aborted foetuses from infected swine herds in the state of sao paulo brazil |
| topic | Pig Abortion Porcine circovirus Porcine parvovirus <it>Brucella</it> |
| url | http://www.actavetscand.com/content/54/1/29 |
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