Targeting Autophagy for the Treatment of Alzheimer’s Disease: Challenges and Opportunities

Targeting Autophagy for the Treatment of Alzheimer’s Disease: Challenges and Opportunities

Alzheimer’s disease (AD) is the most common type of dementia which characterized by a progressive loss of memory and cognitive function due to degeneration of synapses and axons. Currently, there is no cure for AD. Deposition of extracellular amyloid-β (Aβ) plaques and intracellular tau neurofibrill...

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Bibliographic Details
Main Authors: Jie Liu, Lian Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Alzheimer’s disease
autophagy
autophagic vesicle
amyloid-β plaque
tau neurofibrillary tangle
synapse
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00203/full

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