Cleaving HIV-1 provirus from ART-suppressed patient-derived resting CD4 T Cells using Cpf1/crRNA-array ribonucleotide protein packaged by CD4-targeting lentivirus-like particle

Cleaving HIV-1 provirus from ART-suppressed patient-derived resting CD4 T Cells using Cpf1/crRNA-array ribonucleotide protein packaged by CD4-targeting lentivirus-like particle

Bibliographic Details
Main Authors:	W. Hu, Y. Cai, Y. Zhu, F. Li, A.O. Stella, P. Tebas, K. Mounzer, J. Kostman, S. Turville, L. Montaner
Format:	Article
Language:	English
Published:	Elsevier 2019-12-01
Series:	Journal of Virus Eradication
Online Access:	http://www.sciencedirect.com/science/article/pii/S2055664020302211

Similar Items

Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion
by: Ryan D. Chow, et al.
Published: (2018-05-01)

Multiplex gene editing by CRISPR–Cpf1 using a single crRNA array
by: Mohanraju, Prarthana, et al.
Published: (2017)

Chromatin maturation of the HIV-1 provirus in primary resting CD4+ T cells.
by: Birgitta Lindqvist, et al.
Published: (2020-01-01)

Regulation of HIV-1 provirus and CD4+ T cell biology by transcriptional coregulators
by: B.C. Nikolai, et al.
Published: (2017-12-01)

Genome editing of CCR5 by AsCpf1 renders CD4+T cells resistance to HIV-1 infection
by: Zhepeng Liu, et al.
Published: (2020-07-01)

Identification of Genetically Intact HIV-1 Proviruses in Specific CD4+ T Cells from Effectively Treated Participants
by: Bonnie Hiener, et al.
Published: (2017-10-01)

Reactivation of HIV-1 proviruses in immune-compromised mice engrafted with human VOA-negative CD4+ T cells
by: Zhe Yuan, et al.
Published: (2017-01-01)

Zn2+-dependent DNAzymes that cleave all combinations of ribonucleotides
by: Rika Inomata, et al.
Published: (2021-02-01)

Multi-Platform Detection of Small Ruminant Lentivirus Antibodies and Provirus as Biomarkers of Production Losses
by: Irache Echeverría, et al.
Published: (2020-04-01)

PP 4.16 – 00188 Investigating the Role of Naïve CD4+ T-cells as a CTL Resistant Sanctuary for Intact HIV Proviruses
by: J. Weiler, et al.
Published: (2022-12-01)

Persistent HIV-1 transcription in CD4+ T cells from ART-suppressed individuals can originate from biologically competent proviruses
by: M. Vignoles, et al.
Published: (2021-09-01)

Reactivation of VOA-inducible and -uninducible HIV-1 proviruses using immune-compromised mice engrafted with human resting CD4+ T cells
by: Z. Yuan, et al.
Published: (2015-12-01)

Intact proviruses are enriched in the colon and associated with PD-1+TIGIT− mucosal CD4+ T cells of people with HIV-1 on antiretroviral therapyResearch in context
by: Camille Vellas, et al.
Published: (2024-02-01)

Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration.
by: Kajita, M, et al.
Published: (2001)

Cell-associated provirus size decreases in the xenografted CD4 T cells from chronically infected natural host in a novel simianized mice model
by: Z. Yuan, et al.
Published: (2019-12-01)

CD32+ CD4+ T Cells are HIV transcriptionally active rather than a resting reservoir
by: M. Abdel-Mohsen, et al.
Published: (2017-12-01)

In vivo expression of unspliced HIV RNA in expanded CD4+T-cell clones containing defective or replication-competent proviruses
by: M.F. Kearney, et al.
Published: (2015-12-01)

OP 3.3 – 00030 Inducible replication-competent HIV proviruses persist in memory CD4+ T cells expressing high levels of the integrin VLA-4 (α4β1)
by: C. Dufour, et al.
Published: (2022-12-01)

Mobilisation of CPF funds : the CPF investment scheme
by: Bony Chatterjee, et al.
Published: (2008)

Lower HIV provirus levels are associated with more APOBEC3G protein in blood resting memory CD4+ T lymphocytes of controllers in vivo.
by: Mariapia De Pasquale, et al.
Published: (2013-01-01)

Preclinical Development and Clinical-Scale Manufacturing of HIV Gag-Specific, LentivirusModified CD4 T Cells for HIV Functional Cure
by: Haishan Li, et al.
Published: (2020-06-01)

Gene activation in human cells using CRISPR/Cpf1-p300 and CRISPR/Cpf1-SunTag systems
by: Xin Zhang, et al.
Published: (2017-11-01)

Glycosylation of CD4 and Thy-1.
by: Dwek, R, et al.
Published: (1993)

Regulation of CD4⁺ and CD8⁺ effector responses by Sprouty-1.
by: Sam Collins, et al.
Published: (2012-01-01)

Correction to: Gene activation in human cells using CRISPR/Cpf1-p300 and CRISPR/Cpf1-SunTag systems
by: Xin Zhang, et al.
Published: (2018-11-01)

24 Thalidomide reverses latency of HIV-1 provirus
by: S. Samer, et al.
Published: (2016-07-01)

Distinct HIV reservoir measures correlate with defective but not intact pro-viral DNA
by: E. Papasavvas, et al.
Published: (2019-12-01)

HIV-1 proviruses which are integrated into cancer-related genes are inducible
by: A. Varabyou, et al.
Published: (2017-12-01)

Engineered Cpf1 variants with altered PAM specificities
by: Schneider, Martin W, et al.
Published: (2018)

Pooled library screening with multiplexed Cpf1 library
by: Jintan Liu, et al.
Published: (2019-07-01)

Production and characterization of monoclonal antibodies against grass carp CD4-1 and CD4-2
by: Bangjie Wang, et al.
Published: (2024-03-01)

Unequal distribution of genetically-intact HIV-1 proviruses in cells expressing the immune checkpoint markers PD-1 and/or CTLA-4
by: Katie Fisher, et al.
Published: (2023-01-01)

CCR5 Gene Editing of Resting CD4+ T Cells by Transient ZFN Expression From HIV Envelope Pseudotyped Nonintegrating Lentivirus Confers HIV-1 Resistance in Humanized Mice
by: Guohua Yi, et al.
Published: (2014-01-01)

CPF and retirement issues
by: Ee, Florence Yen Yi, et al.
Published: (2008)

Adequacy of CPF for retirement.
by: Hue, Tai Ling., et al.
Published: (2008)

Provision of CPF and retirement.
by: Chong, Khai Chyan., et al.
Published: (2008)

CPF and retirement planning.
by: Loh, Yang Keng., et al.
Published: (2008)

Transcriptional and Epigenetic Regulatory Mechanisms Affecting HTLV-1 Provirus
by: Paola Miyazato, et al.
Published: (2016-06-01)

Increased Platelet-CD4+ T Cell Aggregates Are Correlated With HIV-1 Permissiveness and CD4+ T Cell Loss
by: Xiao-Peng Dai, et al.
Published: (2021-12-01)

Self-organized criticality theory and the expansion of PD-1-positive effector CD4 T cells: search for autoantibody-inducing CD4 (aiCD4) T cells
by: Yumi eMiyazaki, et al.
Published: (2013-04-01)