A Potential Target for Diabetic Vascular Damage: High Glucose-Induced Monocyte Extracellular Vesicles Impair Endothelial Cells by Delivering miR-142-5p

A Potential Target for Diabetic Vascular Damage: High Glucose-Induced Monocyte Extracellular Vesicles Impair Endothelial Cells by Delivering miR-142-5p

Endothelial dysfunction is a key accessory to diabetic cardiovascular complications, and the regulatory role of the extracellular vesicles (EVs) from the innate immune system is growing. We tested whether EVs derived from high glucose-induced monocytes could shuttle microRNAs and impair endothelial...

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Bibliographic Details
Main Authors: Rui Zhang, Shuai Niu, Zhihua Rong, Fengshi Li, Leng Ni, Xiao Di, Changwei Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
diabetes mellitus
extracellular vesicles
monocytes
endothelial damage
miR-142-5p
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.913791/full

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