Microarray-Based Transcriptional Profiling of Renieramycin M and Jorunnamycin C, Isolated from Thai Marine Organisms

Microarray-Based Transcriptional Profiling of Renieramycin M and Jorunnamycin C, Isolated from Thai Marine Organisms

Renieramycin M and jorunnamycin C, two isoquinolinequinone compounds differing only at the C-22 ester side chain, were evaluated for their cytotoxic effects on human colon (HCT116) and breast (MDA-MB-435) cancer cell lines. These two compounds displayed potent cancer cell growth inhibition, their IC...

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Bibliographic Details
Main Authors: Takatoshi Kawai, Takashi Owa, Rie Ushijima-Sugano, Naomi Daikuhara, Masashi Yokoya, Kornvika Charupant, Naoki Saito, Khanit Suwanborirux
Format: Article
Language:English
Published: MDPI AG 2009-10-01
Series:Marine Drugs
Subjects:
renieramycin M
jorunnamycin C
marine sponge
oligonucleotide microarray
antitumor agent
Online Access:http://www.mdpi.com/1660-3397/7/4/483/

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