Lysosomal autophagy promotes recovery in rats with acute knee injury through TFEB mediation

Lysosomal autophagy promotes recovery in rats with acute knee injury through TFEB mediation

Abstract Background To study the role of lysosomal decomposition and elimination of old bone matrix, as well as the mechanism of promoting chondrocyte growth and bone recovery through the perspective of TFEB-mediated lysosomal autophagy. Methods Rat models of acute knee injury were designed, and aut...

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Bibliographic Details
Main Authors: Qingquan Xia, Xuhua Wu, Ke Rong, Zhenyu Zhou, Xujun Li, Teng Fei, Xiaofan Yin
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Acute knee injury
Lysosome
Autophagy
TFEB gene
Online Access:http://link.springer.com/article/10.1186/s13018-020-1573-3

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