A missense variant in FTCD is associated with arsenic metabolism and toxicity phenotypes in Bangladesh.

Inorganic arsenic (iAs) is a carcinogen, and exposure to iAs via food and water is a global public health problem. iAs-contaminated drinking water alone affects >100 million people worldwide, including ~50 million in Bangladesh. Once absorbed into the blood stream, most iAs is converted to mono-m...

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Main Authors: Brandon L Pierce, Lin Tong, Samantha Dean, Maria Argos, Farzana Jasmine, Muhammad Rakibuz-Zaman, Golam Sarwar, Md Tariqul Islam, Hasan Shahriar, Tariqul Islam, Mahfuzar Rahman, Md Yunus, Vincent J Lynch, Devin Oglesbee, Joseph H Graziano, Muhammad G Kibriya, Mary V Gamble, Habibul Ahsan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1007984