Efferocytosis by bone marrow mesenchymal stromal cells disrupts osteoblastic differentiation via mitochondrial remodeling

Efferocytosis by bone marrow mesenchymal stromal cells disrupts osteoblastic differentiation via mitochondrial remodeling

Abstract The efficient clearance of dead and dying cells, efferocytosis, is critical to maintain tissue homeostasis. In the bone marrow microenvironment (BMME), this role is primarily fulfilled by professional bone marrow macrophages, but recent work has shown that mesenchymal stromal cells (MSCs) a...

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Bibliographic Details
Main Authors: Emily R. Quarato, Noah A. Salama, Allison J. Li, Charles O. Smith, Jane Zhang, Yuko Kawano, Matthew McArthur, Jane L. Liesveld, Michael W. Becker, Michael R. Elliott, Roman A. Eliseev, Laura M. Calvi
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05931-9

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