Hair as a Medicolegal Evidence in Detection of Cannabis and Pregabalin residues

            Hair samples are one of the most important resources in the forensic analysis of crime scenes, often providing valuable information that can lead to the identification of a suspect or a victim. This study was conducted to HPTLC quantitative evaluation of Cannabis and Pregabalin residues...

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Main Authors: Sherine Abbas, Rania H. Abdou, Shereen M. Mahmoud, Waleed F., Kawthar A. Elhady
Format: Article
Language:English
Published: Assiut University 2024-01-01
Series:Journal of Advanced Veterinary Research
Subjects:
Online Access:https://advetresearch.com/index.php/AVR/article/view/1676
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author Sherine Abbas
Rania H. Abdou
Shereen M. Mahmoud
Waleed F.
Kawthar A. Elhady
author_facet Sherine Abbas
Rania H. Abdou
Shereen M. Mahmoud
Waleed F.
Kawthar A. Elhady
author_sort Sherine Abbas
collection DOAJ
description             Hair samples are one of the most important resources in the forensic analysis of crime scenes, often providing valuable information that can lead to the identification of a suspect or a victim. This study was conducted to HPTLC quantitative evaluation of Cannabis and Pregabalin residues in hair and serum.  Thirty Wistar male rats were grouped into three groups; first group kept as negative control, second group (Cannabis group) administered Cannabis by gastric tube at a dose of 3 mg/kg b.wt.) and third group (Pregabalin group) administered Pregabalin by gastric tube at a dose of 30 mg/kg b.wt. daily for eight weeks. Results revealed that Cannabis and Pregabalin were both deposited in hair and serum compared with control groups. Using of hair samples is strongly recommended as routine test for pregabalin and cannabis abuse beside blood and urine tests.
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spelling doaj.art-1ac03beb5fae442f9bf06c3d040bf0e22024-01-13T04:48:27ZengAssiut UniversityJournal of Advanced Veterinary Research2090-62692090-62772024-01-011310Hair as a Medicolegal Evidence in Detection of Cannabis and Pregabalin residuesSherine Abbas0Rania H. Abdou1Shereen M. Mahmoud2Waleed F.3Kawthar A. Elhady4Faculty of Veterinary Medicine, Egyptian Chinese University, Cairo, EgyptDepartment of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt.Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt.Department of Pharmacology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt.Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt.             Hair samples are one of the most important resources in the forensic analysis of crime scenes, often providing valuable information that can lead to the identification of a suspect or a victim. This study was conducted to HPTLC quantitative evaluation of Cannabis and Pregabalin residues in hair and serum.  Thirty Wistar male rats were grouped into three groups; first group kept as negative control, second group (Cannabis group) administered Cannabis by gastric tube at a dose of 3 mg/kg b.wt.) and third group (Pregabalin group) administered Pregabalin by gastric tube at a dose of 30 mg/kg b.wt. daily for eight weeks. Results revealed that Cannabis and Pregabalin were both deposited in hair and serum compared with control groups. Using of hair samples is strongly recommended as routine test for pregabalin and cannabis abuse beside blood and urine tests. https://advetresearch.com/index.php/AVR/article/view/1676CannabisHPTLCHairPregabalinSerum
spellingShingle Sherine Abbas
Rania H. Abdou
Shereen M. Mahmoud
Waleed F.
Kawthar A. Elhady
Hair as a Medicolegal Evidence in Detection of Cannabis and Pregabalin residues
Journal of Advanced Veterinary Research
Cannabis
HPTLC
Hair
Pregabalin
Serum
title Hair as a Medicolegal Evidence in Detection of Cannabis and Pregabalin residues
title_full Hair as a Medicolegal Evidence in Detection of Cannabis and Pregabalin residues
title_fullStr Hair as a Medicolegal Evidence in Detection of Cannabis and Pregabalin residues
title_full_unstemmed Hair as a Medicolegal Evidence in Detection of Cannabis and Pregabalin residues
title_short Hair as a Medicolegal Evidence in Detection of Cannabis and Pregabalin residues
title_sort hair as a medicolegal evidence in detection of cannabis and pregabalin residues
topic Cannabis
HPTLC
Hair
Pregabalin
Serum
url https://advetresearch.com/index.php/AVR/article/view/1676
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