Resolution of a Configurationally Stable Hetero[4]helicene

Resolution of a Configurationally Stable Hetero[4]helicene

We have developed an efficient chemical resolution of racemic hydroxy substituted dithia-aza[4]helicenes (DTA[4]H) <b>1(OH)</b> using enantiopure acids as resolving agents. The better diastereomeric separation was achieved on esters prepared with (1<i>S</i>)-(−)-camphanic aci...

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Bibliographic Details
Main Authors: Michela Lupi, Martina Onori, Stefano Menichetti, Sergio Abbate, Giovanna Longhi, Caterina Viglianisi
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
heterohelicene
chirality
resolution
enantiomers
chiroptical
screw-shaped compounds
Online Access:https://www.mdpi.com/1420-3049/27/4/1160

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