PRESERFLO™ Microshunt: 1-Year Results of a 25-Gauge vs. 27-Gauge Needle Tract
<b>Background:</b> The purpose of this study was to evaluate the effectiveness and safety of the PreserFlo™ microshunt (PMS) using a 25-Gauge vs. 27-Gauge needle tract. <b>Methods</b>: This is a prospective postoperative examination of 60 glaucoma eyes that received a PMS. Th...
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| Format: | Article |
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MDPI AG
2024-03-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/13/7/1979 |
| _version_ | 1797212342859071488 |
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| author | Stefan Steiner Hemma Resch Barbara Kiss Clemens Vass |
| author_facet | Stefan Steiner Hemma Resch Barbara Kiss Clemens Vass |
| author_sort | Stefan Steiner |
| collection | DOAJ |
| description | <b>Background:</b> The purpose of this study was to evaluate the effectiveness and safety of the PreserFlo™ microshunt (PMS) using a 25-Gauge vs. 27-Gauge needle tract. <b>Methods</b>: This is a prospective postoperative examination of 60 glaucoma eyes that received a PMS. The main outcome measures were intraocular pressure (IOP), glaucoma drug score (GDS), Kaplan–Meier success rates, complications, and secondary intervention rates. Two subgroups were formed for data comparison: 27-Gauge (27G), and 25-Gauge (25G). Success was defined as IOP < 18 mmHg together with ≥20% IOP reduction with medication allowed (qualified success = QS18) or not (full success = FS18). <b>Results</b>: IOP and GDS were reduced from baseline to the 1-year study visit as follows: All eyes from 23.4 ± 8.6 mmHg (3.1 ± 0.9) to 15.1 ± 5.9 mmHg (0.8 ± 1.1); 25G from 24.2 ± 7.3 mmHg (3.0 ± 0.8) to 12.7 ± 2.7 mmHg (0.5 ± 0.8); and 27G from 23.1 ± 9.2 mmHg (3.1 ± 1.0) to 16.2 ± 6.7 mmHg (0.9 ± 1.2). IOP at one year was lower in the 25G group compared to the 27G group (<i>p</i> = 0.035). Bleb needling was required in eight (13.3%) eyes and open bleb revisions in three (5.0%). Transient hypotony occurred in 21% and choroidal effusion in 8% of all eyes. Choroidal effusions were more frequent in the 25G group (21%) compared to the 27G group (2%, <i>p</i> = 0.031). One-year success rates were significantly higher in the 25G group compared to the 27G group for both QS18 (25G: 67.9% vs. 27G: 35.7%, <i>p</i> = 0.002) and FS18 (25G: 63.6% vs. 27G: 29.2%, <i>p</i> = 0.007). <b>Conclusions</b>: The PreserFlo microshunt is an effective and safe glaucoma surgery with a low rate of bleb revisions or needlings. We show that the 25G needle tract might be more efficient for IOP control at the cost of increased IOP-related complications compared to 27G. |
| first_indexed | 2024-04-24T10:40:52Z |
| format | Article |
| id | doaj.art-1ac54e8ff2884d39b59545574751b170 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-04-24T10:40:52Z |
| publishDate | 2024-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-1ac54e8ff2884d39b59545574751b1702024-04-12T13:21:12ZengMDPI AGJournal of Clinical Medicine2077-03832024-03-01137197910.3390/jcm13071979PRESERFLO™ Microshunt: 1-Year Results of a 25-Gauge vs. 27-Gauge Needle TractStefan Steiner0Hemma Resch1Barbara Kiss2Clemens Vass3Department of Ophthalmology, Medical University of Vienna, 1090 Vienna, AustriaDepartment of Ophthalmology, Sanatorium Hera, 1090 Vienna, AustriaDepartment of Ophthalmology, Medical University of Vienna, 1090 Vienna, AustriaDepartment of Ophthalmology, Medical University of Vienna, 1090 Vienna, Austria<b>Background:</b> The purpose of this study was to evaluate the effectiveness and safety of the PreserFlo™ microshunt (PMS) using a 25-Gauge vs. 27-Gauge needle tract. <b>Methods</b>: This is a prospective postoperative examination of 60 glaucoma eyes that received a PMS. The main outcome measures were intraocular pressure (IOP), glaucoma drug score (GDS), Kaplan–Meier success rates, complications, and secondary intervention rates. Two subgroups were formed for data comparison: 27-Gauge (27G), and 25-Gauge (25G). Success was defined as IOP < 18 mmHg together with ≥20% IOP reduction with medication allowed (qualified success = QS18) or not (full success = FS18). <b>Results</b>: IOP and GDS were reduced from baseline to the 1-year study visit as follows: All eyes from 23.4 ± 8.6 mmHg (3.1 ± 0.9) to 15.1 ± 5.9 mmHg (0.8 ± 1.1); 25G from 24.2 ± 7.3 mmHg (3.0 ± 0.8) to 12.7 ± 2.7 mmHg (0.5 ± 0.8); and 27G from 23.1 ± 9.2 mmHg (3.1 ± 1.0) to 16.2 ± 6.7 mmHg (0.9 ± 1.2). IOP at one year was lower in the 25G group compared to the 27G group (<i>p</i> = 0.035). Bleb needling was required in eight (13.3%) eyes and open bleb revisions in three (5.0%). Transient hypotony occurred in 21% and choroidal effusion in 8% of all eyes. Choroidal effusions were more frequent in the 25G group (21%) compared to the 27G group (2%, <i>p</i> = 0.031). One-year success rates were significantly higher in the 25G group compared to the 27G group for both QS18 (25G: 67.9% vs. 27G: 35.7%, <i>p</i> = 0.002) and FS18 (25G: 63.6% vs. 27G: 29.2%, <i>p</i> = 0.007). <b>Conclusions</b>: The PreserFlo microshunt is an effective and safe glaucoma surgery with a low rate of bleb revisions or needlings. We show that the 25G needle tract might be more efficient for IOP control at the cost of increased IOP-related complications compared to 27G.https://www.mdpi.com/2077-0383/13/7/1979PreserFlomicroshuntMIGSglaucoma surgeryfiltering surgeryglaucoma |
| spellingShingle | Stefan Steiner Hemma Resch Barbara Kiss Clemens Vass PRESERFLO™ Microshunt: 1-Year Results of a 25-Gauge vs. 27-Gauge Needle Tract Journal of Clinical Medicine PreserFlo microshunt MIGS glaucoma surgery filtering surgery glaucoma |
| title | PRESERFLO™ Microshunt: 1-Year Results of a 25-Gauge vs. 27-Gauge Needle Tract |
| title_full | PRESERFLO™ Microshunt: 1-Year Results of a 25-Gauge vs. 27-Gauge Needle Tract |
| title_fullStr | PRESERFLO™ Microshunt: 1-Year Results of a 25-Gauge vs. 27-Gauge Needle Tract |
| title_full_unstemmed | PRESERFLO™ Microshunt: 1-Year Results of a 25-Gauge vs. 27-Gauge Needle Tract |
| title_short | PRESERFLO™ Microshunt: 1-Year Results of a 25-Gauge vs. 27-Gauge Needle Tract |
| title_sort | preserflo™ microshunt 1 year results of a 25 gauge vs 27 gauge needle tract |
| topic | PreserFlo microshunt MIGS glaucoma surgery filtering surgery glaucoma |
| url | https://www.mdpi.com/2077-0383/13/7/1979 |
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