Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion.
Real-time shear-wave elastography (SWE) is a newly developed method which can obtain the stiffness of tissues and organs based on tracking of shear wave propagation through a structure. Several studies have demonstrated its potential in the differentiation between diseased and normal tissue in clini...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4575189?pdf=render |
| _version_ | 1817979814104006656 |
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| author | Zhenxing Sun Mingxing Xie Feixiang Xiang Yue Song Cheng Yu Yanrong Zhang Sachin Ramdhany Jing Wang |
| author_facet | Zhenxing Sun Mingxing Xie Feixiang Xiang Yue Song Cheng Yu Yanrong Zhang Sachin Ramdhany Jing Wang |
| author_sort | Zhenxing Sun |
| collection | DOAJ |
| description | Real-time shear-wave elastography (SWE) is a newly developed method which can obtain the stiffness of tissues and organs based on tracking of shear wave propagation through a structure. Several studies have demonstrated its potential in the differentiation between diseased and normal tissue in clinical practices, however the applicability to testicular disease has not been well elucidated. We investigated the feasibility and reproducibility of SWE in the detection of testicular torsion. This prospective study comprised 15 patients with complete testicular torsion. Results obtained from SWE along with conventional gray-scale and color Doppler sonography and post-operative pathology were compared. The results revealed that (i) the size of injured testis was increased and the twisted testis parenchyma was heterogeneous. The blood flow signals in injured testis were barely visible or absent; (ii) The Young's modulus, including Emean, Emax, Emin and SD values in the border area of torsional testis were higher than those of normal testis (Emean, 78.07±9.01 kPa vs 22.0±5.10 kPa; Emax, 94.07±6.53 kPa vs 27.87±5.78 kPa; Emin, 60.73±7.84 kPa vs 18.90±4.39 kPa; SD, 7.67±0.60 kPa vs 2.30±0.36 kPa, [P<0.05]); The Emax and SD values in the central area of the torsional testis were higher than the corresponding area of the normal testis (Emax, 8.23±0.30 kPa vs 3.97±0.95 kPa; SD, 1.5±0.26 kPa vs 0.67±0.35 kPa,[P<0.05]) and Emin values was lower than those of normal testicles (0.93±0.51 kPa vs 1.6±0.36 kPa; [P<0.05]); (iii) The Young's modulus measurement between two physicians showed good agreement. The pathological findings were accordance with SWE measurement. SWE is a non-invasive, convenient and high reproducible method and may serve as an important alternative tool in the diagnosis and monitoring the progression of the acute scrotums, in additional to conventional Doppler sonography. |
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| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-13T22:47:12Z |
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| spelling | doaj.art-1ac5d24309c1471d8dd50e33dbad6cfb2022-12-22T02:26:21ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01109e013852310.1371/journal.pone.0138523Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion.Zhenxing SunMingxing XieFeixiang XiangYue SongCheng YuYanrong ZhangSachin RamdhanyJing WangReal-time shear-wave elastography (SWE) is a newly developed method which can obtain the stiffness of tissues and organs based on tracking of shear wave propagation through a structure. Several studies have demonstrated its potential in the differentiation between diseased and normal tissue in clinical practices, however the applicability to testicular disease has not been well elucidated. We investigated the feasibility and reproducibility of SWE in the detection of testicular torsion. This prospective study comprised 15 patients with complete testicular torsion. Results obtained from SWE along with conventional gray-scale and color Doppler sonography and post-operative pathology were compared. The results revealed that (i) the size of injured testis was increased and the twisted testis parenchyma was heterogeneous. The blood flow signals in injured testis were barely visible or absent; (ii) The Young's modulus, including Emean, Emax, Emin and SD values in the border area of torsional testis were higher than those of normal testis (Emean, 78.07±9.01 kPa vs 22.0±5.10 kPa; Emax, 94.07±6.53 kPa vs 27.87±5.78 kPa; Emin, 60.73±7.84 kPa vs 18.90±4.39 kPa; SD, 7.67±0.60 kPa vs 2.30±0.36 kPa, [P<0.05]); The Emax and SD values in the central area of the torsional testis were higher than the corresponding area of the normal testis (Emax, 8.23±0.30 kPa vs 3.97±0.95 kPa; SD, 1.5±0.26 kPa vs 0.67±0.35 kPa,[P<0.05]) and Emin values was lower than those of normal testicles (0.93±0.51 kPa vs 1.6±0.36 kPa; [P<0.05]); (iii) The Young's modulus measurement between two physicians showed good agreement. The pathological findings were accordance with SWE measurement. SWE is a non-invasive, convenient and high reproducible method and may serve as an important alternative tool in the diagnosis and monitoring the progression of the acute scrotums, in additional to conventional Doppler sonography.http://europepmc.org/articles/PMC4575189?pdf=render |
| spellingShingle | Zhenxing Sun Mingxing Xie Feixiang Xiang Yue Song Cheng Yu Yanrong Zhang Sachin Ramdhany Jing Wang Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion. PLoS ONE |
| title | Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion. |
| title_full | Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion. |
| title_fullStr | Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion. |
| title_full_unstemmed | Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion. |
| title_short | Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion. |
| title_sort | utility of real time shear wave elastography in the assessment of testicular torsion |
| url | http://europepmc.org/articles/PMC4575189?pdf=render |
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