Mobile phone radiation might alter gene expression in the oral squamous epithelial cells
Abstract Background Accumulating evidence has shown that radiofrequency radiation (RFR) emitted by mobile phones is a potential factor for DNA damage. Whether RFR affects the gene expression of human genes still requires further research. This may help in understanding the mechanisms of action of th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-01-01
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| Series: | Egyptian Journal of Medical Human Genetics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43042-022-00231-x |
| _version_ | 1819280453737119744 |
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| author | Ahmad M. Khalil Khaled M. Al-Qaoud Israa F. Alemam Mohammad A. Okour |
| author_facet | Ahmad M. Khalil Khaled M. Al-Qaoud Israa F. Alemam Mohammad A. Okour |
| author_sort | Ahmad M. Khalil |
| collection | DOAJ |
| description | Abstract Background Accumulating evidence has shown that radiofrequency radiation (RFR) emitted by mobile phones is a potential factor for DNA damage. Whether RFR affects the gene expression of human genes still requires further research. This may help in understanding the mechanisms of action of this radiation. On the assumption that expression of BAMBI and Survivin in the oral squamous epithelial cells might be modified in response to RF electromagnetic field (RF-EMF) exposure, the current study was conducted on a group of young university student volunteers. Results Statistical analysis of the RT-PCR data indicated that no significant association (P value ˃ 0.05) exists between the expression of either gene, and neither the length of history nor the frequency of the phone use. Conclusions Although no clear RF-EMF signature on gene expression could be detected in this in this preliminary study, it is one of the few studies indicating that molecular-level changes might take place in humans in response to chronic mobile phone EMR exposure. Further investigations in this field are warranted. |
| first_indexed | 2024-12-24T00:44:03Z |
| format | Article |
| id | doaj.art-1ac62ab808a9427da810104adc23790f |
| institution | Directory Open Access Journal |
| issn | 2090-2441 |
| language | English |
| last_indexed | 2024-12-24T00:44:03Z |
| publishDate | 2022-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Egyptian Journal of Medical Human Genetics |
| spelling | doaj.art-1ac62ab808a9427da810104adc23790f2022-12-21T17:23:51ZengSpringerOpenEgyptian Journal of Medical Human Genetics2090-24412022-01-012311710.1186/s43042-022-00231-xMobile phone radiation might alter gene expression in the oral squamous epithelial cellsAhmad M. Khalil0Khaled M. Al-Qaoud1Israa F. Alemam2Mohammad A. Okour3Department of Biological Sciences, Yarmouk UniversityDepartment of Biological Sciences, Yarmouk UniversityDepartment of Biological Sciences, Yarmouk UniversityDepartment of Biological Sciences, Yarmouk UniversityAbstract Background Accumulating evidence has shown that radiofrequency radiation (RFR) emitted by mobile phones is a potential factor for DNA damage. Whether RFR affects the gene expression of human genes still requires further research. This may help in understanding the mechanisms of action of this radiation. On the assumption that expression of BAMBI and Survivin in the oral squamous epithelial cells might be modified in response to RF electromagnetic field (RF-EMF) exposure, the current study was conducted on a group of young university student volunteers. Results Statistical analysis of the RT-PCR data indicated that no significant association (P value ˃ 0.05) exists between the expression of either gene, and neither the length of history nor the frequency of the phone use. Conclusions Although no clear RF-EMF signature on gene expression could be detected in this in this preliminary study, it is one of the few studies indicating that molecular-level changes might take place in humans in response to chronic mobile phone EMR exposure. Further investigations in this field are warranted.https://doi.org/10.1186/s43042-022-00231-xBAMBI geneGene expressionMobile phoneOral squamous epithelial cellsRadiofrequency radiationSurvivin |
| spellingShingle | Ahmad M. Khalil Khaled M. Al-Qaoud Israa F. Alemam Mohammad A. Okour Mobile phone radiation might alter gene expression in the oral squamous epithelial cells Egyptian Journal of Medical Human Genetics BAMBI gene Gene expression Mobile phone Oral squamous epithelial cells Radiofrequency radiation Survivin |
| title | Mobile phone radiation might alter gene expression in the oral squamous epithelial cells |
| title_full | Mobile phone radiation might alter gene expression in the oral squamous epithelial cells |
| title_fullStr | Mobile phone radiation might alter gene expression in the oral squamous epithelial cells |
| title_full_unstemmed | Mobile phone radiation might alter gene expression in the oral squamous epithelial cells |
| title_short | Mobile phone radiation might alter gene expression in the oral squamous epithelial cells |
| title_sort | mobile phone radiation might alter gene expression in the oral squamous epithelial cells |
| topic | BAMBI gene Gene expression Mobile phone Oral squamous epithelial cells Radiofrequency radiation Survivin |
| url | https://doi.org/10.1186/s43042-022-00231-x |
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