Fractal Analysis and FEM Assessment of Soft Tissue Affected by Fibrosis

This research shows an image processing method to determine the liver tissue’s mechanical behavior under physiological damage caused by fibrosis pathology. The proposed method consists of using a liver tissue CAD/CAE model obtained from a tomography of the human abdomen, where the diaphragmatic surf...

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Main Authors: Arturo Yishai Prieto-Vázquez, Alejandro Cuautle-Estrada, Mario Alberto Grave-Capistrán, Octavio Ramírez, Christopher René Torres-SanMiguel
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Fractal and Fractional
Subjects:
Online Access:https://www.mdpi.com/2504-3110/7/9/661
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author Arturo Yishai Prieto-Vázquez
Alejandro Cuautle-Estrada
Mario Alberto Grave-Capistrán
Octavio Ramírez
Christopher René Torres-SanMiguel
author_facet Arturo Yishai Prieto-Vázquez
Alejandro Cuautle-Estrada
Mario Alberto Grave-Capistrán
Octavio Ramírez
Christopher René Torres-SanMiguel
author_sort Arturo Yishai Prieto-Vázquez
collection DOAJ
description This research shows an image processing method to determine the liver tissue’s mechanical behavior under physiological damage caused by fibrosis pathology. The proposed method consists of using a liver tissue CAD/CAE model obtained from a tomography of the human abdomen, where the diaphragmatic surface of this tissue is compressed by a moving flat surface. For this work, two tools were created—the first to analyze the deformations and the second to analyze the displacements of the liver tissue. Gibbon and MATLAB<sup>®</sup> were used for numerical analysis with the FEBio computer program. Although deformation in the scenario can be treated as an orthogonal coordinate system, the relationship between the total change in height (measured) and the deformation was obtained. The outcomes show liver tissue behavior as a hyperelastic model; the Mooney–Rivlin mathematical characterization model was proposed in this case. Another method to determine the level of physiological damage caused by fibrosis is fractal analysis. This work used the Hausdorff fractal dimension (HFD) method to calculate and analyze the 2D topological surface.
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spelling doaj.art-1ac8431236da41f48eab182b008d756d2023-11-19T10:48:26ZengMDPI AGFractal and Fractional2504-31102023-08-017966110.3390/fractalfract7090661Fractal Analysis and FEM Assessment of Soft Tissue Affected by FibrosisArturo Yishai Prieto-Vázquez0Alejandro Cuautle-Estrada1Mario Alberto Grave-Capistrán2Octavio Ramírez3Christopher René Torres-SanMiguel4Instituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Zacatenco Edificio, Mexico City 07738, MexicoInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Zacatenco Edificio, Mexico City 07738, MexicoInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Zacatenco Edificio, Mexico City 07738, MexicoInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Zacatenco Edificio, Mexico City 07738, MexicoInstituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Zacatenco Edificio, Mexico City 07738, MexicoThis research shows an image processing method to determine the liver tissue’s mechanical behavior under physiological damage caused by fibrosis pathology. The proposed method consists of using a liver tissue CAD/CAE model obtained from a tomography of the human abdomen, where the diaphragmatic surface of this tissue is compressed by a moving flat surface. For this work, two tools were created—the first to analyze the deformations and the second to analyze the displacements of the liver tissue. Gibbon and MATLAB<sup>®</sup> were used for numerical analysis with the FEBio computer program. Although deformation in the scenario can be treated as an orthogonal coordinate system, the relationship between the total change in height (measured) and the deformation was obtained. The outcomes show liver tissue behavior as a hyperelastic model; the Mooney–Rivlin mathematical characterization model was proposed in this case. Another method to determine the level of physiological damage caused by fibrosis is fractal analysis. This work used the Hausdorff fractal dimension (HFD) method to calculate and analyze the 2D topological surface.https://www.mdpi.com/2504-3110/7/9/661liver tissuefibrosishyperelastic modelHausdorff distancesJaccard indexfractals
spellingShingle Arturo Yishai Prieto-Vázquez
Alejandro Cuautle-Estrada
Mario Alberto Grave-Capistrán
Octavio Ramírez
Christopher René Torres-SanMiguel
Fractal Analysis and FEM Assessment of Soft Tissue Affected by Fibrosis
Fractal and Fractional
liver tissue
fibrosis
hyperelastic model
Hausdorff distances
Jaccard index
fractals
title Fractal Analysis and FEM Assessment of Soft Tissue Affected by Fibrosis
title_full Fractal Analysis and FEM Assessment of Soft Tissue Affected by Fibrosis
title_fullStr Fractal Analysis and FEM Assessment of Soft Tissue Affected by Fibrosis
title_full_unstemmed Fractal Analysis and FEM Assessment of Soft Tissue Affected by Fibrosis
title_short Fractal Analysis and FEM Assessment of Soft Tissue Affected by Fibrosis
title_sort fractal analysis and fem assessment of soft tissue affected by fibrosis
topic liver tissue
fibrosis
hyperelastic model
Hausdorff distances
Jaccard index
fractals
url https://www.mdpi.com/2504-3110/7/9/661
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AT marioalbertogravecapistran fractalanalysisandfemassessmentofsofttissueaffectedbyfibrosis
AT octavioramirez fractalanalysisandfemassessmentofsofttissueaffectedbyfibrosis
AT christopherrenetorressanmiguel fractalanalysisandfemassessmentofsofttissueaffectedbyfibrosis