Therapeutic Functions of Stem Cells from Oral Cavity: An Update
Adult stem cells have been developed as therapeutics for tissue regeneration and immune regulation due to their self-renewing, differentiating, and paracrine functions. Recently, a variety of adult stem cells from the oral cavity have been discovered, and these dental stem cells mostly exhibit the c...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-06-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/21/12/4389 |
| _version_ | 1797564638118805504 |
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| author | Ji Won Yang Ye Young Shin Yoojin Seo Hyung-Sik Kim |
| author_facet | Ji Won Yang Ye Young Shin Yoojin Seo Hyung-Sik Kim |
| author_sort | Ji Won Yang |
| collection | DOAJ |
| description | Adult stem cells have been developed as therapeutics for tissue regeneration and immune regulation due to their self-renewing, differentiating, and paracrine functions. Recently, a variety of adult stem cells from the oral cavity have been discovered, and these dental stem cells mostly exhibit the characteristics of mesenchymal stem cells (MSCs). Dental MSCs can be applied for the replacement of dental and oral tissues against various tissue-damaging conditions including dental caries, periodontitis, and oral cancers, as well as for systemic regulation of excessive inflammation in immune disorders, such as autoimmune diseases and hypersensitivity. Therefore, in this review, we summarized and updated the types of dental stem cells and their functions to exert therapeutic efficacy against diseases. |
| first_indexed | 2024-03-10T19:00:55Z |
| format | Article |
| id | doaj.art-1acd38773db8408fae070d00e57c5402 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T19:00:55Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-1acd38773db8408fae070d00e57c54022023-11-20T04:25:34ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-06-012112438910.3390/ijms21124389Therapeutic Functions of Stem Cells from Oral Cavity: An UpdateJi Won Yang0Ye Young Shin1Yoojin Seo2Hyung-Sik Kim3Department of Life Science in Dentistry, School of Dentistry, Pusan National University, Yangsan 50612, KoreaDepartment of Life Science in Dentistry, School of Dentistry, Pusan National University, Yangsan 50612, KoreaDental and Life Science Institute, Pusan National University, Yangsan 50612, KoreaDepartment of Life Science in Dentistry, School of Dentistry, Pusan National University, Yangsan 50612, KoreaAdult stem cells have been developed as therapeutics for tissue regeneration and immune regulation due to their self-renewing, differentiating, and paracrine functions. Recently, a variety of adult stem cells from the oral cavity have been discovered, and these dental stem cells mostly exhibit the characteristics of mesenchymal stem cells (MSCs). Dental MSCs can be applied for the replacement of dental and oral tissues against various tissue-damaging conditions including dental caries, periodontitis, and oral cancers, as well as for systemic regulation of excessive inflammation in immune disorders, such as autoimmune diseases and hypersensitivity. Therefore, in this review, we summarized and updated the types of dental stem cells and their functions to exert therapeutic efficacy against diseases.https://www.mdpi.com/1422-0067/21/12/4389dental mesenchymal stem cellsoral cavityperiodontitisregenerationimmunomodulation |
| spellingShingle | Ji Won Yang Ye Young Shin Yoojin Seo Hyung-Sik Kim Therapeutic Functions of Stem Cells from Oral Cavity: An Update International Journal of Molecular Sciences dental mesenchymal stem cells oral cavity periodontitis regeneration immunomodulation |
| title | Therapeutic Functions of Stem Cells from Oral Cavity: An Update |
| title_full | Therapeutic Functions of Stem Cells from Oral Cavity: An Update |
| title_fullStr | Therapeutic Functions of Stem Cells from Oral Cavity: An Update |
| title_full_unstemmed | Therapeutic Functions of Stem Cells from Oral Cavity: An Update |
| title_short | Therapeutic Functions of Stem Cells from Oral Cavity: An Update |
| title_sort | therapeutic functions of stem cells from oral cavity an update |
| topic | dental mesenchymal stem cells oral cavity periodontitis regeneration immunomodulation |
| url | https://www.mdpi.com/1422-0067/21/12/4389 |
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