Cardiovascular Involvement in Fabry’s Disease: New Advances in Diagnostic Strategies, Outcome Prediction and Management
Cardiovascular involvement is common in Fabry’s disease and is the leading cause of morbidity and mortality. The research is focused on identifying diagnostic clues suggestive of cardiovascular involvement in the preclinical stage of the disease through clinical and imaging markers. Different pathop...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Radcliffe Medical Media
2023-08-01
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| Series: | Cardiac Failure Review |
| Online Access: | https://www.cfrjournal.com/articleindex/cfr.2023.06 |
| _version_ | 1797199964820996096 |
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| author | Emanuele Monda Luigi Falco Giuseppe Palmiero Marta Rubino Alessia Perna Gaetano Diana Federica Verrillo Francesca Dongiglio Annapaola Cirillo Adelaide Fusco Martina Caiazza Giuseppe Limongelli |
| author_facet | Emanuele Monda Luigi Falco Giuseppe Palmiero Marta Rubino Alessia Perna Gaetano Diana Federica Verrillo Francesca Dongiglio Annapaola Cirillo Adelaide Fusco Martina Caiazza Giuseppe Limongelli |
| author_sort | Emanuele Monda |
| collection | DOAJ |
| description | Cardiovascular involvement is common in Fabry’s disease and is the leading cause of morbidity and mortality. The research is focused on identifying diagnostic clues suggestive of cardiovascular involvement in the preclinical stage of the disease through clinical and imaging markers. Different pathophysiologically driven therapies are currently or will soon be available for the treatment of Fabry’s disease, with the most significant benefit observed in the early stages of the disease. Thus, early diagnosis and risk stratification for adverse outcomes are crucial to determine when to start an aetiological treatment. This review describes the cardiovascular involvement in Fabry’s disease, focusing on the advances in diagnostic strategies, outcome prediction and disease management. |
| first_indexed | 2024-03-07T17:39:41Z |
| format | Article |
| id | doaj.art-1acd54e7de48464d8ca34ed8d9690b83 |
| institution | Directory Open Access Journal |
| issn | 2057-7540 2057-7559 |
| language | English |
| last_indexed | 2024-04-24T07:24:07Z |
| publishDate | 2023-08-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | Cardiac Failure Review |
| spelling | doaj.art-1acd54e7de48464d8ca34ed8d9690b832024-04-20T16:03:35ZengRadcliffe Medical MediaCardiac Failure Review2057-75402057-75592023-08-01910.15420/cfr.2023.06Cardiovascular Involvement in Fabry’s Disease: New Advances in Diagnostic Strategies, Outcome Prediction and ManagementEmanuele Monda0Luigi Falco1Giuseppe Palmiero2Marta Rubino3Alessia Perna4Gaetano Diana5Federica Verrillo6Francesca Dongiglio7Annapaola Cirillo8Adelaide Fusco9Martina Caiazza10Giuseppe Limongelli11Inherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, Italy; Institute of Cardiovascular Science, University College London, London, UKInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, ItalyInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, ItalyInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, ItalyInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, ItalyInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, ItalyInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, ItalyInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, ItalyInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, ItalyInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, ItalyInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, ItalyInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania “Luigi Vanvitelli”, Monaldi Hospital, Naples, Italy; Institute of Cardiovascular Science, University College London, London, UKCardiovascular involvement is common in Fabry’s disease and is the leading cause of morbidity and mortality. The research is focused on identifying diagnostic clues suggestive of cardiovascular involvement in the preclinical stage of the disease through clinical and imaging markers. Different pathophysiologically driven therapies are currently or will soon be available for the treatment of Fabry’s disease, with the most significant benefit observed in the early stages of the disease. Thus, early diagnosis and risk stratification for adverse outcomes are crucial to determine when to start an aetiological treatment. This review describes the cardiovascular involvement in Fabry’s disease, focusing on the advances in diagnostic strategies, outcome prediction and disease management.https://www.cfrjournal.com/articleindex/cfr.2023.06 |
| spellingShingle | Emanuele Monda Luigi Falco Giuseppe Palmiero Marta Rubino Alessia Perna Gaetano Diana Federica Verrillo Francesca Dongiglio Annapaola Cirillo Adelaide Fusco Martina Caiazza Giuseppe Limongelli Cardiovascular Involvement in Fabry’s Disease: New Advances in Diagnostic Strategies, Outcome Prediction and Management Cardiac Failure Review |
| title | Cardiovascular Involvement in Fabry’s Disease: New Advances in Diagnostic Strategies, Outcome Prediction and Management |
| title_full | Cardiovascular Involvement in Fabry’s Disease: New Advances in Diagnostic Strategies, Outcome Prediction and Management |
| title_fullStr | Cardiovascular Involvement in Fabry’s Disease: New Advances in Diagnostic Strategies, Outcome Prediction and Management |
| title_full_unstemmed | Cardiovascular Involvement in Fabry’s Disease: New Advances in Diagnostic Strategies, Outcome Prediction and Management |
| title_short | Cardiovascular Involvement in Fabry’s Disease: New Advances in Diagnostic Strategies, Outcome Prediction and Management |
| title_sort | cardiovascular involvement in fabry s disease new advances in diagnostic strategies outcome prediction and management |
| url | https://www.cfrjournal.com/articleindex/cfr.2023.06 |
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