Cardiovascular comorbidities of rheumatoid arthritis in Taiwanese adults: A retrospective single-center study

Objective: To evaluate the association between rheumatoid arthritis (RA) and cardiovascular comorbidities, including hyperlipidemia, hypertension, and diabetes, in Taiwanese patients based on the data from medical records. Materials and Methods: A retrospective study was performed using the computer...

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Main Authors: Ning-Sheng Lai, Chun-Lung Wang, Ming-Chi Lu, Malcolm Koo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Tzu-Chi Medical Journal
Subjects:
Online Access:http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2017;volume=29;issue=3;spage=171;epage=173;aulast=Lai
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author Ning-Sheng Lai
Chun-Lung Wang
Ming-Chi Lu
Malcolm Koo
author_facet Ning-Sheng Lai
Chun-Lung Wang
Ming-Chi Lu
Malcolm Koo
author_sort Ning-Sheng Lai
collection DOAJ
description Objective: To evaluate the association between rheumatoid arthritis (RA) and cardiovascular comorbidities, including hyperlipidemia, hypertension, and diabetes, in Taiwanese patients based on the data from medical records. Materials and Methods: A retrospective study was performed using the computerized medical records from a regional hospital located in southern Taiwan. A total of 2293 patients (age range 30–79 years) with a diagnosis of RA (International Classification of Diseases, Ninth Revision, Clinical Modification code 714.0) treated since the opening of the study hospital in July 2000 until February 2013 were included. The RA cases were frequency matched for age and sex with 9172 patients without RA. The associations of RA with hyperlipidemia, hypertension, and diabetes were evaluated using multiple logistic regression analysis. Results: Significant associations between RA and hyperlipidemia (adjusted odds ratio [OR] = 2.05, 95% confidence interval [CI] = 1.77–2.38,P< 0.001) and hypertension (adjusted OR = 2.76, 95% CI = 2.43–3.14,P< 0.001) were observed. However, diabetes was not significantly associated with RA in either male or female patients. Conclusion: Findings from this retrospective medical record study indicated that hyperlipidemia and hypertension were significant cardiovascular comorbidities of RA.
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spelling doaj.art-1acdf08da84747b1af94dbe44b1c08fc2022-12-22T02:38:10ZengWolters Kluwer Medknow PublicationsTzu-Chi Medical Journal1016-31902223-89562017-01-0129317117310.4103/tcmj.tcmj_62_17Cardiovascular comorbidities of rheumatoid arthritis in Taiwanese adults: A retrospective single-center studyNing-Sheng LaiChun-Lung WangMing-Chi LuMalcolm KooObjective: To evaluate the association between rheumatoid arthritis (RA) and cardiovascular comorbidities, including hyperlipidemia, hypertension, and diabetes, in Taiwanese patients based on the data from medical records. Materials and Methods: A retrospective study was performed using the computerized medical records from a regional hospital located in southern Taiwan. A total of 2293 patients (age range 30–79 years) with a diagnosis of RA (International Classification of Diseases, Ninth Revision, Clinical Modification code 714.0) treated since the opening of the study hospital in July 2000 until February 2013 were included. The RA cases were frequency matched for age and sex with 9172 patients without RA. The associations of RA with hyperlipidemia, hypertension, and diabetes were evaluated using multiple logistic regression analysis. Results: Significant associations between RA and hyperlipidemia (adjusted odds ratio [OR] = 2.05, 95% confidence interval [CI] = 1.77–2.38,P< 0.001) and hypertension (adjusted OR = 2.76, 95% CI = 2.43–3.14,P< 0.001) were observed. However, diabetes was not significantly associated with RA in either male or female patients. Conclusion: Findings from this retrospective medical record study indicated that hyperlipidemia and hypertension were significant cardiovascular comorbidities of RA.http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2017;volume=29;issue=3;spage=171;epage=173;aulast=LaiHyperlipidemiasHypertensionMedical recordsRheumatoid arthritis
spellingShingle Ning-Sheng Lai
Chun-Lung Wang
Ming-Chi Lu
Malcolm Koo
Cardiovascular comorbidities of rheumatoid arthritis in Taiwanese adults: A retrospective single-center study
Tzu-Chi Medical Journal
Hyperlipidemias
Hypertension
Medical records
Rheumatoid arthritis
title Cardiovascular comorbidities of rheumatoid arthritis in Taiwanese adults: A retrospective single-center study
title_full Cardiovascular comorbidities of rheumatoid arthritis in Taiwanese adults: A retrospective single-center study
title_fullStr Cardiovascular comorbidities of rheumatoid arthritis in Taiwanese adults: A retrospective single-center study
title_full_unstemmed Cardiovascular comorbidities of rheumatoid arthritis in Taiwanese adults: A retrospective single-center study
title_short Cardiovascular comorbidities of rheumatoid arthritis in Taiwanese adults: A retrospective single-center study
title_sort cardiovascular comorbidities of rheumatoid arthritis in taiwanese adults a retrospective single center study
topic Hyperlipidemias
Hypertension
Medical records
Rheumatoid arthritis
url http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2017;volume=29;issue=3;spage=171;epage=173;aulast=Lai
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AT chunlungwang cardiovascularcomorbiditiesofrheumatoidarthritisintaiwaneseadultsaretrospectivesinglecenterstudy
AT mingchilu cardiovascularcomorbiditiesofrheumatoidarthritisintaiwaneseadultsaretrospectivesinglecenterstudy
AT malcolmkoo cardiovascularcomorbiditiesofrheumatoidarthritisintaiwaneseadultsaretrospectivesinglecenterstudy