Hepatitis C virus protects human B lymphocytes from Fas-mediated apoptosis via E2-CD81 engagement.
HCV infection is often associated with B-cell regulatory control disturbance and delayed appearance of neutralizing antibodies. CD81 is a cellular receptor for HCV and can bind to HCV envelope protein 2 (E2). CD81 also participates to form a B cell costimulatory complex. To investigate whether HCV i...
Asıl Yazarlar: | , , , , , , , , , , , |
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Materyal Türü: | Makale |
Dil: | English |
Baskı/Yayın Bilgisi: |
Public Library of Science (PLoS)
2011-04-01
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Seri Bilgileri: | PLoS ONE |
Online Erişim: | http://europepmc.org/articles/PMC3079738?pdf=render |