The Analysis of Patients Admitted to the Emergency Department Due to Complications Related to Warfarin Treatment

Objective: Warfarin is the most commonly used oral anticoagulant around the world. The most important complication of warfarin is bleeding. This study was conducted to evaluate the patients who were admitted to our emergency department due to complications related to warfarin treatment.Material and...

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Main Authors: Mustafa Burak Sayhan, Serhat Oğuz, Volkan Yüksel, Serhat Hüseyin, Esin Seçgin Sayhan, Gökçe Yağcı
Format: Article
Language:English
Published: Galenos Yayinevi 2014-12-01
Series:Eurasian Journal of Emergency Medicine
Subjects:
Online Access: http://eajem.galenos.com.tr/archives/archive-detail/article-preview/the-analysis-of-patients-admitted-to-the-emergency/21936
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author Mustafa Burak Sayhan
Serhat Oğuz
Volkan Yüksel
Serhat Hüseyin
Esin Seçgin Sayhan
Gökçe Yağcı
author_facet Mustafa Burak Sayhan
Serhat Oğuz
Volkan Yüksel
Serhat Hüseyin
Esin Seçgin Sayhan
Gökçe Yağcı
author_sort Mustafa Burak Sayhan
collection DOAJ
description Objective: Warfarin is the most commonly used oral anticoagulant around the world. The most important complication of warfarin is bleeding. This study was conducted to evaluate the patients who were admitted to our emergency department due to complications related to warfarin treatment.Material and Methods: Eighty-nine patients (32 females, 57 males) were enrolled into this retrospective study. The patients were evaluated according to their age, gender, duration of therapy (year), co-administered drugs, bleeding localization, treatments, amount of blood transfusions, duration of bleeding, initial and after-treatment PT, INR, complete blood count, and aPTT.Results: Mean duration of anticoagulant use was 3.05±2.87 years. The most common indication of warfarin was atrial fibrillation. The most frequent bleeding localization was the upper gastrointestinal tract. Thirty-four (38.2%) of the patients had major bleeding, and 55 (61.8%) had minor bleeding. Age, co-administered drugs, amount of erythrocyte suspension transfusion, presence of previous warfarin overdose history, Hb levels at admission, and duration of follow-up in the ED were different between the bleeding types.Conclusion: In this study, we found that the bleeding complications of warfarin were associated with the aged population, presence of previous warfarin overdose history, and concomitant drug use.
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spelling doaj.art-1acf57d26bfd4dc799712862605002562023-02-15T16:17:00ZengGalenos YayineviEurasian Journal of Emergency Medicine2149-58072149-60482014-12-0113419419810.5152/jaem.2014.07513049054The Analysis of Patients Admitted to the Emergency Department Due to Complications Related to Warfarin TreatmentMustafa Burak Sayhan0Serhat Oğuz1Volkan Yüksel2Serhat Hüseyin3Esin Seçgin Sayhan4Gökçe Yağcı5 Department of Emergeny Medicine, Trakya University Medical School, Edirne, Turkey Department of General Surgery, Trakya University Medical School Edirne, Turkey Department of Cardiovascular Surgery, Trakya University Medical School, Edirne, Turkey Department of Cardiovascular Surgery, Trakya University Medical School, Edirne, Turkey Department of Public Health, Trakya Üniversitesi Medical School, Edirne, Turkey Department of Emergeny Medicine, Trakya University Medical School, Edirne, Turkey Objective: Warfarin is the most commonly used oral anticoagulant around the world. The most important complication of warfarin is bleeding. This study was conducted to evaluate the patients who were admitted to our emergency department due to complications related to warfarin treatment.Material and Methods: Eighty-nine patients (32 females, 57 males) were enrolled into this retrospective study. The patients were evaluated according to their age, gender, duration of therapy (year), co-administered drugs, bleeding localization, treatments, amount of blood transfusions, duration of bleeding, initial and after-treatment PT, INR, complete blood count, and aPTT.Results: Mean duration of anticoagulant use was 3.05±2.87 years. The most common indication of warfarin was atrial fibrillation. The most frequent bleeding localization was the upper gastrointestinal tract. Thirty-four (38.2%) of the patients had major bleeding, and 55 (61.8%) had minor bleeding. Age, co-administered drugs, amount of erythrocyte suspension transfusion, presence of previous warfarin overdose history, Hb levels at admission, and duration of follow-up in the ED were different between the bleeding types.Conclusion: In this study, we found that the bleeding complications of warfarin were associated with the aged population, presence of previous warfarin overdose history, and concomitant drug use. http://eajem.galenos.com.tr/archives/archive-detail/article-preview/the-analysis-of-patients-admitted-to-the-emergency/21936 Oral anticoagulant treatmentwarfarinbleedingemergency department
spellingShingle Mustafa Burak Sayhan
Serhat Oğuz
Volkan Yüksel
Serhat Hüseyin
Esin Seçgin Sayhan
Gökçe Yağcı
The Analysis of Patients Admitted to the Emergency Department Due to Complications Related to Warfarin Treatment
Eurasian Journal of Emergency Medicine
Oral anticoagulant treatment
warfarin
bleeding
emergency department
title The Analysis of Patients Admitted to the Emergency Department Due to Complications Related to Warfarin Treatment
title_full The Analysis of Patients Admitted to the Emergency Department Due to Complications Related to Warfarin Treatment
title_fullStr The Analysis of Patients Admitted to the Emergency Department Due to Complications Related to Warfarin Treatment
title_full_unstemmed The Analysis of Patients Admitted to the Emergency Department Due to Complications Related to Warfarin Treatment
title_short The Analysis of Patients Admitted to the Emergency Department Due to Complications Related to Warfarin Treatment
title_sort analysis of patients admitted to the emergency department due to complications related to warfarin treatment
topic Oral anticoagulant treatment
warfarin
bleeding
emergency department
url http://eajem.galenos.com.tr/archives/archive-detail/article-preview/the-analysis-of-patients-admitted-to-the-emergency/21936
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