Bilateral Corneal Ghost Vessels in an Otherwise Healthy Child
We report a rare case of bilateral corneal ghost vessels in a 6–year-old child with an unremarkable past ocular and past medical history. This study was a single observational case report. A 6-year-old girl was referred to our clinic for further evaluation, due to suboptimal visual acuity in both ey...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2021-10-01
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| Series: | Case Reports in Clinical Practice |
| Subjects: | |
| Online Access: | https://crcp.tums.ac.ir/index.php/crcp/article/view/393 |
| _version_ | 1819290206884331520 |
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| author | Acieh Es'haghi Hossein Aghaei Shirin Rafatnia Sanam Alilou |
| author_facet | Acieh Es'haghi Hossein Aghaei Shirin Rafatnia Sanam Alilou |
| author_sort | Acieh Es'haghi |
| collection | DOAJ |
| description | We report a rare case of bilateral corneal ghost vessels in a 6–year-old child with an unremarkable past ocular and past medical history. This study was a single observational case report. A 6-year-old girl was referred to our clinic for further evaluation, due to suboptimal visual acuity in both eyes. Her past medical and ocular history revealed no systemic, inflammatory, infectious, or degenerative disorders. Slit-lamp examination revealed regressed blood vessels (“ghost vessels”) in the anterior and mid-corneal stroma as the only pathologic finding. Confocal scanning microscopy of both corneas demonstrated scattered branching railroad-shaped ghost vessels at the level of the middle and anterior stroma. Complete systemic workup was performed for the patient. No identifiable risk factor for the development of corneal vascularization was found. According to our findings, we assume that in our patient, vasculogenesis occurred due to angioblast invasion to the presumptive cornea due to disequilibrium in mechanisms involved in vascular patterning during embryonic development. |
| first_indexed | 2024-12-24T03:19:04Z |
| format | Article |
| id | doaj.art-1ad1da11ef1041d9a1de2d68d069bb37 |
| institution | Directory Open Access Journal |
| issn | 2538-2683 2538-2691 |
| language | English |
| last_indexed | 2024-12-24T03:19:04Z |
| publishDate | 2021-10-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Case Reports in Clinical Practice |
| spelling | doaj.art-1ad1da11ef1041d9a1de2d68d069bb372022-12-21T17:17:32ZengTehran University of Medical SciencesCase Reports in Clinical Practice2538-26832538-26912021-10-016310.18502/crcp.v6i3.7127Bilateral Corneal Ghost Vessels in an Otherwise Healthy ChildAcieh Es'haghi0Hossein Aghaei1Shirin Rafatnia2Sanam Alilou3Eye Research Center, The Five Senses Insttute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.Eye Research Center, The Five Senses Insttute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.AND. Department of Ophthalmology, Imam Hossein Medical Center, Shahid Behesht University of Medical Sciences, Tehran, Iran.Student Research Commitee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.Student Research Commitee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.We report a rare case of bilateral corneal ghost vessels in a 6–year-old child with an unremarkable past ocular and past medical history. This study was a single observational case report. A 6-year-old girl was referred to our clinic for further evaluation, due to suboptimal visual acuity in both eyes. Her past medical and ocular history revealed no systemic, inflammatory, infectious, or degenerative disorders. Slit-lamp examination revealed regressed blood vessels (“ghost vessels”) in the anterior and mid-corneal stroma as the only pathologic finding. Confocal scanning microscopy of both corneas demonstrated scattered branching railroad-shaped ghost vessels at the level of the middle and anterior stroma. Complete systemic workup was performed for the patient. No identifiable risk factor for the development of corneal vascularization was found. According to our findings, we assume that in our patient, vasculogenesis occurred due to angioblast invasion to the presumptive cornea due to disequilibrium in mechanisms involved in vascular patterning during embryonic development.https://crcp.tums.ac.ir/index.php/crcp/article/view/393Corneal neovascularizatonCorneal angiogenesisAngioblastAntangiogenic agents |
| spellingShingle | Acieh Es'haghi Hossein Aghaei Shirin Rafatnia Sanam Alilou Bilateral Corneal Ghost Vessels in an Otherwise Healthy Child Case Reports in Clinical Practice Corneal neovascularizaton Corneal angiogenesis Angioblast Antangiogenic agents |
| title | Bilateral Corneal Ghost Vessels in an Otherwise Healthy Child |
| title_full | Bilateral Corneal Ghost Vessels in an Otherwise Healthy Child |
| title_fullStr | Bilateral Corneal Ghost Vessels in an Otherwise Healthy Child |
| title_full_unstemmed | Bilateral Corneal Ghost Vessels in an Otherwise Healthy Child |
| title_short | Bilateral Corneal Ghost Vessels in an Otherwise Healthy Child |
| title_sort | bilateral corneal ghost vessels in an otherwise healthy child |
| topic | Corneal neovascularizaton Corneal angiogenesis Angioblast Antangiogenic agents |
| url | https://crcp.tums.ac.ir/index.php/crcp/article/view/393 |
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