Experimental benznidazole treatment of Trypanosoma cruzi II strains isolated from children of the Jequitinhonha Valley, Minas Gerais, Brazil, with Chagas disease

Experimental benznidazole treatment of Trypanosoma cruzi II strains isolated from children of the Jequitinhonha Valley, Minas Gerais, Brazil, with Chagas disease

Trypanosoma cruzi strains from distinct geographic areas show differences in drug resistance and association between parasites genetic and treatment response has been observed. Considering that benznidazole (BZ) can reduce the parasite burden and tissues damage, even in not cured animals and individ...

Full description

Bibliographic Details
Main Authors:	Jaquelline Carla Valamiel de Oliveira-Silva, Girley Francisco Machado-de-Assis, Maykon Tavares Oliveira, Nívia Carolina Noguieira Paiva, Márcio Sobreira Silva Araújo, Cláudia Martins Carneiro, Olindo Assis Martins-Filho, Helen Rodrigues Martins, Marta de Lana
Format:	Article
Language:	English
Published:	Fundação Oswaldo Cruz (FIOCRUZ) 2015-02-01
Series:	Memorias do Instituto Oswaldo Cruz
Subjects:	Trypanosoma cruzi II benznidazole response acute and chronic phases murine model Jequitinhonha Valley MG Brazil
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000100086&lng=en&tlng=en

Similar Items

Molecular and biological characterization of Trypanosoma cruzi strains isolated from children from Jequitinhonha Valley, State of Minas Gerais, Brazil
by: Jaquelline Carla Valamiel de Oliveira e Silva, et al.
Published: (2013-07-01)

Trypanosoma cruzi Discret Typing Units (TcII and TcVI) in samples of patients from two municipalities of the Jequitinhonha Valley, MG, Brazil, using two molecular typing strategies
by: Maykon Tavares de Oliveira, et al.
Published: (2015-10-01)

Tolerance and Adherence of Patients with Chronic Chagas Disease Treated with Benznidazole
by: Cristina Vázquez, et al.
Published: (2023-01-01)

Benznidazole Treatment: Time- and Dose-Dependence Varies with the <i>Trypanosoma cruzi</i> Strain
by: Kátia da Silva Fonseca, et al.
Published: (2021-06-01)

Variation in susceptibility to benznidazole in isolates derived from Trypanosoma cruzi parental strains
by: Veloso VM, et al.
Published: (2001-01-01)

Transcriptomic analysis of benznidazole-resistant and susceptible Trypanosoma cruzi populations
by: Davi Alvarenga Lima, et al.
Published: (2023-05-01)

Parasitemia and antibody response to benznidazole treatment in a cohort of patients with chronic Chagas disease
by: Carlos Henrique Valente Moreira, et al.
Published: (2023-09-01)

Evaluation of parasitemia by qPCR in patients with chronic Chagas disease treated with benznidazole
by: Bianca Sabaini Pavan Tycha, et al.
Published: (2023-01-01)

Mixed T Helper1/T Helper2/T Cytotoxic Profile in Subjects with Chronic Chagas Disease with Hypersensitivity Reactions to Benznidazole
by: Melisa D. Castro Eiro, et al.
Published: (2022-08-01)

A serological, parasitological and clinical evaluation of untreated Chagas disease patients and those treated with benznidazole before and thirteen years after intervention
by: Girley Francisco Machado-de-Assis, et al.
Published: (2013-11-01)

Benznidazole and amiodarone combined treatment attenuates cytoskeletal damage in Trypanosoma cruzi-infected cardiac cells
by: Juliana Magalhães Chaves Barbosa, et al.
Published: (2022-08-01)

Evaluation of in vitro anti-Trypanosoma cruzi activity of medications benznidazole, amiodarone hydrochloride, and their combination
by: Angela Maria Lourenço, et al.

Trypanosoma cruzi: susceptibility to chemotherapy with benznidazole of clones isolated from the highly resistant Colombian strain
by: Edson L.P. Camandaroba, et al.
Published: (2003-04-01)

Miltefosine and Benznidazole Combination Improve Anti-Trypanosoma cruzi In Vitro and In Vivo Efficacy
by: Julián Ernesto Nicolás Gulin, et al.
Published: (2022-07-01)

Trypanosoma cruzi benznidazole susceptibility in vitro does not predict the therapeutic outcome of human Chagas disease
by: Margoth Moreno, et al.
Published: (2010-11-01)

Treatment With Suboptimal Dose of Benznidazole Mitigates Immune Response Molecular Pathways in Mice With Chronic Chagas Cardiomyopathy
by: Priscila Silva Grijó Farani, et al.
Published: (2021-07-01)

HIDROGEOLOGIA DA REGIÃO DE ARAÇUAÍ, NO MÉDIO VALE DO RIO JEQUITINHONHA-MG
by: Fernando Roberto de Oliveira, et al.
Published: (2000-09-01)

LEVANTAMENTO HIDROGEOLÓGICO DA ÁREA DE ARAÇUAÍ NO MÉDIO VALE DO JEQUITINHONHA-MG
by: Fernando Roberto de Oliveira, et al.
Published: (2002-12-01)

Treatment with benznidazole in association with immunosuppressive drugs in mice chronically infected with Trypanosoma cruzi: investigation into the possible development of neoplasias
by: Sonia G. Andrade, et al.
Published: (2003-07-01)

Trypanocidal activity of genotoxic concentration of benznidazole on epimastigote forms of Trypanosoma cruzi = Atividade tripanocida da concentração genotóxica do benzonidazol em formas epimastigotas de Trypanosoma cruzi
by: Edilson Nobuyoshi Kaneshima, et al.
Published: (2012-10-01)

Synthesis of Silver Nanoparticle Employing Corn Cob Xylan as a Reducing Agent with Anti-Trypanosoma cruzi Activity
by: Brito TK, et al.
Published: (2020-02-01)

Effect of tripanosomicide benznidazole (Rochagan®) on the biodistribution of sodium pertechnetate (Na99mTcO4) in Wistar rats
by: Vanessa Santos de Arruda Barbosa, et al.
Published: (2008-12-01)

Trypanosoma cruzi: parasite antigens sequestered in heart interstitial dendritic cells are related to persisting myocarditis in benznidazole-treated mice
by: Renata Siqueira Portella, et al.
Published: (2009-11-01)

Poly-ε-Caprolactone Implants for Benznidazole Prolonged Release: An Alternative to Chagas Disease Oral Treatment
by: Ana Lia Mazzeti, et al.
Published: (2023-04-01)

A novel ABCG-like transporter of Trypanosoma cruzi is involved in natural resistance to benznidazole
by: Bianca Zingales, et al.
Published: (2015-05-01)

Nifurtimox versus benznidazole or placebo for asymptomatic Trypanosoma cruzi infection (Equivalence of Usual Interventions for Trypanosomiasis - EQUITY): study protocol for a randomised controlled trial
by: Juan Carlos Villar, et al.
Published: (2019-07-01)

Susceptibilidad in vitro a hexadecilfosfocolina (miltefosina), nifurtimox y benznidazole de cepas de Trypanosoma cruzi aisladas en Santander, Colombia
by: Patricia Escobar, et al.
Published: (2009-09-01)

Domiciliation of Triatoma pseudomaculata (Corrêa e Espínola 1964) in the Jequitinhonha Valley, State of Minas Gerais Domiciliação de Triatoma pseudomaculata (Corrêa e Espínola 1964) no Vale do Jequitinhonha, Estado de Minas Gerais
by: Girley Francisco Machado de Assis, et al.
Published: (2007-08-01)

Benznidazole therapy for Chagas disease in asymptomatic Trypanosoma cruzi -seropositive former blood donors: evaluation of the efficacy of different treatment regimens
by: André Pires Antunes, et al.

Overexpression of eukaryotic initiation factor 5A (eIF5A) affects susceptibility to benznidazole in Trypanosoma cruzi populations
by: Douglas de Souza Moreira, et al.
Published: (2018-07-01)

Reações adversas em pacientes com doença de Chagas tratados com benzonidazol, no Estado do Ceará Adverse reactions in Chagas disease patients treated with benznidazole, in the State of Ceará
by: Vânia Maria Oliveira de Pontes, et al.
Published: (2010-04-01)

Uneventful benznidazole treatment of acute Chagas disease during pregnancy: a case report
by: Valeria Rita Corrêa, et al.
Published: (2014-06-01)

Enfermedad de Chagas aguda, en un adulto tratado con benznidazol (Rochagan®) en Costa Rica
by: Víctor M. Montenegro, et al.
Published: (2004-06-01)

Enfermedad de Chagas aguda, en un adulto tratado con benznidazol (Rochagan®) en Costa Rica
by: Víctor M. Montenegro, et al.
Published: (2004-06-01)

Pharmacokinetic and pharmacodynamic responses in adult patients with Chagas disease treated with a new formulation of benznidazole
by: Marisa Liliana Fernández, et al.
Published: (2016-03-01)

VALE DO JEQUITINHONHA: MIGRAÇÕES TEMPORÁRIAS E SUPEREXPLORAÇÃO DA FORÇA DE TRABALHO | Jequitinhonha Valley: temporary migrations and overexploration of the workforce
by: Cristiane Luíza Sabino de Souza, et al.
Published: (2018-02-01)

Short-course Benznidazole treatment to reduce Trypanosoma cruzi parasitic load in women of reproductive age (BETTY): a non-inferiority randomized controlled trial study protocol
by: María L. Cafferata, et al.
Published: (2020-08-01)

In Vitro Benznidazole and Nifurtimox Susceptibility Profile of Trypanosoma cruzi Strains Belonging to Discrete Typing Units TcI, TcII, and TcV
by: Susana Revollo, et al.
Published: (2019-10-01)

Caracterização físico-química do fármaco antichagásico benznidazol Physicochemical characterization of antichagasic benznidazole
by: Flávia Pires Maximiano, et al.
Published: (2010-01-01)

Response to chemotherapy with benznidazole of clones isolated from the 21SF strain of Trypanosoma cruzi (biodeme Type II, Trypanosoma cruzi II) Resposta à quimioterapia com benzonidazol de clones isolados da cepa 21SF do Trypanosoma cruzi (biodema Tipo II, Trypanosoma cruzi II)
by: Rozália Figueira Campos, et al.
Published: (2005-04-01)