Sublingual Misoprostol for Unsatisfactory Colposcopic Finding: A randomized controlled trial
Objectives: To assess the effectiveness of 200 μg sublingual misoprostol for converting an unsatisfactory to satisfactory colposcopic finding.Materials and Methods: Forty-two participants with abnormal cervical cytology and unsatisfactory colposcopic finding who underwent colposcopy b...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Royal Thai College of Obstetricians and Gynaecologists
2018-09-01
|
| Series: | Thai Journal of Obstetrics and Gynaecology |
| Subjects: | |
| Online Access: | https://tci-thaijo.org/index.php/tjog/article/download/97433/111936/ |
| _version_ | 1819027505579819008 |
|---|---|
| author | Sasitorn Wongart Maleechat Sripipattanakul Thumwadee Tangsiriwatthana Sukanda Mahaweerawat |
| author_facet | Sasitorn Wongart Maleechat Sripipattanakul Thumwadee Tangsiriwatthana Sukanda Mahaweerawat |
| author_sort | Sasitorn Wongart |
| collection | DOAJ |
| description | Objectives: To assess the effectiveness of 200 μg sublingual misoprostol for converting an unsatisfactory to satisfactory colposcopic finding.Materials and Methods: Forty-two participants with abnormal cervical cytology and unsatisfactory colposcopic finding who underwent colposcopy between September 2016 and June 2017 were randomized into two groups; either misoprostol or placebo given sublingually. Second colposcopy was performed 2 hours later, and the conversion rate of unsatisfactory to satisfactory colposcopic finding of both groups was analyzed.Results: Baseline characteristics were similar between two groups. Conversion rate of unsatisfactory to satisfactory colposcopic finding in participants who received sublingual misoprostol was statistically significant higher than placebo group (80.9% vs 38.1%, p = 0.011, relative risk = 2.1, 95% confidence interval 1.18-3.80). There was no significant difference in adverse effect between groups.Conclusion: Two hundred micrograms of sublingual misoprostol, 2 hours before performing colposcopy can convert an unsatisfactory finding to a satisfactory one. |
| first_indexed | 2024-12-21T05:43:32Z |
| format | Article |
| id | doaj.art-1ad6c2d14f3e416db790e3dc8c10a4a0 |
| institution | Directory Open Access Journal |
| issn | 0857-6084 0857-6084 |
| language | English |
| last_indexed | 2024-12-21T05:43:32Z |
| publishDate | 2018-09-01 |
| publisher | The Royal Thai College of Obstetricians and Gynaecologists |
| record_format | Article |
| series | Thai Journal of Obstetrics and Gynaecology |
| spelling | doaj.art-1ad6c2d14f3e416db790e3dc8c10a4a02022-12-21T19:14:12ZengThe Royal Thai College of Obstetricians and GynaecologistsThai Journal of Obstetrics and Gynaecology0857-60840857-60842018-09-01263198204https://doi.org/10.14456/tjog.2018.22Sublingual Misoprostol for Unsatisfactory Colposcopic Finding: A randomized controlled trialSasitorn Wongart0Maleechat Sripipattanakul1Thumwadee Tangsiriwatthana2Sukanda Mahaweerawat3Department of Obstetrics and Gynecology, Khon Kaen Hospital, Khon Kaen 40000, ThailandDepartment of Obstetrics and Gynecology, Khon Kaen Hospital, Khon Kaen 40000, ThailandDepartment of Obstetrics and Gynecology, Khon Kaen Hospital, Khon Kaen 40000, ThailandDepartment of Obstetrics and Gynecology, Khon Kaen Hospital, Khon Kaen 40000, ThailandObjectives: To assess the effectiveness of 200 μg sublingual misoprostol for converting an unsatisfactory to satisfactory colposcopic finding.Materials and Methods: Forty-two participants with abnormal cervical cytology and unsatisfactory colposcopic finding who underwent colposcopy between September 2016 and June 2017 were randomized into two groups; either misoprostol or placebo given sublingually. Second colposcopy was performed 2 hours later, and the conversion rate of unsatisfactory to satisfactory colposcopic finding of both groups was analyzed.Results: Baseline characteristics were similar between two groups. Conversion rate of unsatisfactory to satisfactory colposcopic finding in participants who received sublingual misoprostol was statistically significant higher than placebo group (80.9% vs 38.1%, p = 0.011, relative risk = 2.1, 95% confidence interval 1.18-3.80). There was no significant difference in adverse effect between groups.Conclusion: Two hundred micrograms of sublingual misoprostol, 2 hours before performing colposcopy can convert an unsatisfactory finding to a satisfactory one.https://tci-thaijo.org/index.php/tjog/article/download/97433/111936/unsatisfactory colposcopyabnormal pap smearsublingual misoprostol |
| spellingShingle | Sasitorn Wongart Maleechat Sripipattanakul Thumwadee Tangsiriwatthana Sukanda Mahaweerawat Sublingual Misoprostol for Unsatisfactory Colposcopic Finding: A randomized controlled trial Thai Journal of Obstetrics and Gynaecology unsatisfactory colposcopy abnormal pap smear sublingual misoprostol |
| title | Sublingual Misoprostol for Unsatisfactory Colposcopic Finding: A randomized controlled trial |
| title_full | Sublingual Misoprostol for Unsatisfactory Colposcopic Finding: A randomized controlled trial |
| title_fullStr | Sublingual Misoprostol for Unsatisfactory Colposcopic Finding: A randomized controlled trial |
| title_full_unstemmed | Sublingual Misoprostol for Unsatisfactory Colposcopic Finding: A randomized controlled trial |
| title_short | Sublingual Misoprostol for Unsatisfactory Colposcopic Finding: A randomized controlled trial |
| title_sort | sublingual misoprostol for unsatisfactory colposcopic finding a randomized controlled trial |
| topic | unsatisfactory colposcopy abnormal pap smear sublingual misoprostol |
| url | https://tci-thaijo.org/index.php/tjog/article/download/97433/111936/ |
| work_keys_str_mv | AT sasitornwongart sublingualmisoprostolforunsatisfactorycolposcopicfindingarandomizedcontrolledtrial AT maleechatsripipattanakul sublingualmisoprostolforunsatisfactorycolposcopicfindingarandomizedcontrolledtrial AT thumwadeetangsiriwatthana sublingualmisoprostolforunsatisfactorycolposcopicfindingarandomizedcontrolledtrial AT sukandamahaweerawat sublingualmisoprostolforunsatisfactorycolposcopicfindingarandomizedcontrolledtrial |