Preparation of a new nanocolloid radiopharmaceutical based on aluminum oxide
The authors have studied the regularities of 99mТс (VII) adsorption on activated gamma-oxide Al2O3. The paper demonstrates that oxide radionuclide sorption capacity depends on its acid treatment. The reduction process of 99mТс (VII) to 99mТс (IV) with bivalent tin Sn (II) was studied to determine it...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Tomsk Polytechnic University
2009-06-01
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| Series: | Известия Томского политехнического университета: Инжиниринг георесурсов |
| Subjects: | |
| Online Access: | http://izvestiya.tpu.ru/archive/article/view/1128 |
| Summary: | The authors have studied the regularities of 99mТс (VII) adsorption on activated gamma-oxide Al2O3. The paper demonstrates that oxide radionuclide sorption capacity depends on its acid treatment. The reduction process of 99mТс (VII) to 99mТс (IV) with bivalent tin Sn (II) was studied to determine its required and sufficient amount which could maintain full 99mТс "reducibliness" in the reaction mixture. The adsorption of 99mТс reduced on nanosized powder of aluminum gamma-oxide was investigated; and the technique for preparing 99mТс (IV)-Al2O3 nanocolloids was developed. The authors carried out the preliminary biomedical tests of 99mТс (IV)-Al2O3 compounds in animals to determine functional ability to radionuclide imaging of lymph glands. |
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| ISSN: | 2500-1019 2413-1830 |