Electrospun PVA Fibers for Drug Delivery: A Review

Innovation in biomedical science is always a field of interest for researchers. Drug delivery, being one of the key areas of biomedical science, has gained considerable significance. The utilization of simple yet effective techniques such as electrospinning has undergone significant development in t...

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Main Authors: Fatima T. Zahra, Quincy Quick, Richard Mu
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/15/18/3837
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author Fatima T. Zahra
Quincy Quick
Richard Mu
author_facet Fatima T. Zahra
Quincy Quick
Richard Mu
author_sort Fatima T. Zahra
collection DOAJ
description Innovation in biomedical science is always a field of interest for researchers. Drug delivery, being one of the key areas of biomedical science, has gained considerable significance. The utilization of simple yet effective techniques such as electrospinning has undergone significant development in the field of drug delivery. Various polymers such as PEG (polyethylene glycol), PLGA (Poly(lactic-co-glycolic acid)), PLA(Polylactic acid), and PCA (poly(methacrylate citric acid)) have been utilized to prepare electrospinning-based drug delivery systems (DDSs). Polyvinyl alcohol (PVA) has recently gained attention because of its biocompatibility, biodegradability, non-toxicity, and ideal mechanical properties as these are the key factors in developing DDSs. Moreover, it has shown promising results in developing DDSs individually and when combined with natural and synthetic polymers such as chitosan and polycaprolactone (PCL). Considering the outstanding properties of PVA, the aim of this review paper was therefore to summarize these recent advances by highlighting the potential of electrospun PVA for drug delivery systems.
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spelling doaj.art-1adbfae7d52f4d3488b9085a090b32bd2023-11-19T12:36:32ZengMDPI AGPolymers2073-43602023-09-011518383710.3390/polym15183837Electrospun PVA Fibers for Drug Delivery: A ReviewFatima T. Zahra0Quincy Quick1Richard Mu2TIGER Institute, Tennessee State University, Nashville, TN 37209, USADepartment of Biological Sciences, Tennessee State University, Nashville, TN 37209, USATIGER Institute, Tennessee State University, Nashville, TN 37209, USAInnovation in biomedical science is always a field of interest for researchers. Drug delivery, being one of the key areas of biomedical science, has gained considerable significance. The utilization of simple yet effective techniques such as electrospinning has undergone significant development in the field of drug delivery. Various polymers such as PEG (polyethylene glycol), PLGA (Poly(lactic-co-glycolic acid)), PLA(Polylactic acid), and PCA (poly(methacrylate citric acid)) have been utilized to prepare electrospinning-based drug delivery systems (DDSs). Polyvinyl alcohol (PVA) has recently gained attention because of its biocompatibility, biodegradability, non-toxicity, and ideal mechanical properties as these are the key factors in developing DDSs. Moreover, it has shown promising results in developing DDSs individually and when combined with natural and synthetic polymers such as chitosan and polycaprolactone (PCL). Considering the outstanding properties of PVA, the aim of this review paper was therefore to summarize these recent advances by highlighting the potential of electrospun PVA for drug delivery systems.https://www.mdpi.com/2073-4360/15/18/3837electrospinningpolyvinyl alcohol (PVA)nanofibersdrug deliverywound dressingtransdermal
spellingShingle Fatima T. Zahra
Quincy Quick
Richard Mu
Electrospun PVA Fibers for Drug Delivery: A Review
Polymers
electrospinning
polyvinyl alcohol (PVA)
nanofibers
drug delivery
wound dressing
transdermal
title Electrospun PVA Fibers for Drug Delivery: A Review
title_full Electrospun PVA Fibers for Drug Delivery: A Review
title_fullStr Electrospun PVA Fibers for Drug Delivery: A Review
title_full_unstemmed Electrospun PVA Fibers for Drug Delivery: A Review
title_short Electrospun PVA Fibers for Drug Delivery: A Review
title_sort electrospun pva fibers for drug delivery a review
topic electrospinning
polyvinyl alcohol (PVA)
nanofibers
drug delivery
wound dressing
transdermal
url https://www.mdpi.com/2073-4360/15/18/3837
work_keys_str_mv AT fatimatzahra electrospunpvafibersfordrugdeliveryareview
AT quincyquick electrospunpvafibersfordrugdeliveryareview
AT richardmu electrospunpvafibersfordrugdeliveryareview