Mutations and Protein Interaction Landscape Reveal Key Cellular Events Perturbed in Upper Motor Neurons with HSP and PLS

Hereditary spastic paraplegia (HSP) and primary lateral sclerosis (PLS) are rare motor neuron diseases, which affect mostly the upper motor neurons (UMNs) in patients. The UMNs display early vulnerability and progressive degeneration, while other cortical neurons mostly remain functional. Identifica...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Oge Gozutok, Benjamin Ryan Helmold, P. Hande Ozdinler
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: MDPI AG 2021-04-01
Цуврал:Brain Sciences
Нөхцлүүд:
Онлайн хандалт:https://www.mdpi.com/2076-3425/11/5/578