Spontaneous Charge Generation in Flowing Albumin Solutions at 35 °C and 38 °C
The time dependence of a charge accumulation in a 10−15 M albumin solution, flowing through a measuring cell of an analytical flow system injector, had a nonlinear character under certain conditions, within a human physiological temperature range. Sharp charge increases depended on albumin concentra...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-12-01
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| Series: | Biosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6374/7/4/60 |
| _version_ | 1818912435511230464 |
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| author | Yuri D. Ivanov Andrey F. Kozlov Rafael A. Galiullin Ekaterina F. Kolesanova Tatyana O. Pleshakova |
| author_facet | Yuri D. Ivanov Andrey F. Kozlov Rafael A. Galiullin Ekaterina F. Kolesanova Tatyana O. Pleshakova |
| author_sort | Yuri D. Ivanov |
| collection | DOAJ |
| description | The time dependence of a charge accumulation in a 10−15 M albumin solution, flowing through a measuring cell of an analytical flow system injector, had a nonlinear character under certain conditions, within a human physiological temperature range. Sharp charge increases depended on albumin concentration. This effect must be taken into consideration when generating models that describe electrokinetic phenomena in flowing protein solutions and when developing analytical flow systems for the registration of biomolecules in low concentration ranges. |
| first_indexed | 2024-12-19T23:14:33Z |
| format | Article |
| id | doaj.art-1adf949b28344bebb693cc2a80ee4165 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-12-19T23:14:33Z |
| publishDate | 2017-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-1adf949b28344bebb693cc2a80ee41652022-12-21T20:02:08ZengMDPI AGBiosensors2079-63742017-12-01746010.3390/bios7040060bios7040060Spontaneous Charge Generation in Flowing Albumin Solutions at 35 °C and 38 °CYuri D. Ivanov0Andrey F. Kozlov1Rafael A. Galiullin2Ekaterina F. Kolesanova3Tatyana O. Pleshakova4Institute of Biomedical Chemistry, 119121 Moscow, RussiaInstitute of Biomedical Chemistry, 119121 Moscow, RussiaInstitute of Biomedical Chemistry, 119121 Moscow, RussiaInstitute of Biomedical Chemistry, 119121 Moscow, RussiaInstitute of Biomedical Chemistry, 119121 Moscow, RussiaThe time dependence of a charge accumulation in a 10−15 M albumin solution, flowing through a measuring cell of an analytical flow system injector, had a nonlinear character under certain conditions, within a human physiological temperature range. Sharp charge increases depended on albumin concentration. This effect must be taken into consideration when generating models that describe electrokinetic phenomena in flowing protein solutions and when developing analytical flow systems for the registration of biomolecules in low concentration ranges.https://www.mdpi.com/2079-6374/7/4/60analytical flow-through systemsflowing protein solutioncharge accumulationserum albuminphysiological temperature |
| spellingShingle | Yuri D. Ivanov Andrey F. Kozlov Rafael A. Galiullin Ekaterina F. Kolesanova Tatyana O. Pleshakova Spontaneous Charge Generation in Flowing Albumin Solutions at 35 °C and 38 °C Biosensors analytical flow-through systems flowing protein solution charge accumulation serum albumin physiological temperature |
| title | Spontaneous Charge Generation in Flowing Albumin Solutions at 35 °C and 38 °C |
| title_full | Spontaneous Charge Generation in Flowing Albumin Solutions at 35 °C and 38 °C |
| title_fullStr | Spontaneous Charge Generation in Flowing Albumin Solutions at 35 °C and 38 °C |
| title_full_unstemmed | Spontaneous Charge Generation in Flowing Albumin Solutions at 35 °C and 38 °C |
| title_short | Spontaneous Charge Generation in Flowing Albumin Solutions at 35 °C and 38 °C |
| title_sort | spontaneous charge generation in flowing albumin solutions at 35 °c and 38 °c |
| topic | analytical flow-through systems flowing protein solution charge accumulation serum albumin physiological temperature |
| url | https://www.mdpi.com/2079-6374/7/4/60 |
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