Optogenetic control of NOTCH1 signaling

Optogenetic control of NOTCH1 signaling

Abstract The Notch signaling pathway is a crucial regulator of cell differentiation as well as tissue organization, whose deregulation is linked to the pathogenesis of different diseases. NOTCH1 plays a key role in breast cancer progression by increasing proliferation, maintenance of cancer stem cel...

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Bibliographic Details
Main Authors: Joanna Kałafut, Jakub Czapiński, Alicja Przybyszewska-Podstawka, Arkadiusz Czerwonka, Adrian Odrzywolski, Cecilia Sahlgren, Adolfo Rivero-Müller
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Cell Communication and Signaling
Subjects:
Optogenetics
Notch signaling
NOTCH1
Light-activation
Breast cancer
Online Access:https://doi.org/10.1186/s12964-022-00885-5

Internet

https://doi.org/10.1186/s12964-022-00885-5

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