An empirical Bayes model for gene expression and methylation profiles in antiestrogen resistant breast cancer

An empirical Bayes model for gene expression and methylation profiles in antiestrogen resistant breast cancer

<p>Abstract</p> <p>Background</p> <p>The nuclear transcription factor estrogen receptor alpha (ER-alpha) is the target of several antiestrogen therapeutic agents for breast cancer. However, many ER-alpha positive patients do not respond to these treatments from the begi...

Full description

Bibliographic Details
Main Authors:	Huang Tim, Nephew Kenneth P, Liu Yunlong, Li Lang, Jeong Jaesik, Shen Changyu
Format:	Article
Language:	English
Published:	BMC 2010-11-01
Series:	BMC Medical Genomics
Online Access:	http://www.biomedcentral.com/1755-8794/3/55

Similar Items

Poly-ADP-Ribosylation of Estrogen Receptor-Alpha by PARP1 Mediates Antiestrogen Resistance in Human Breast Cancer Cells
by: Nicholas Pulliam, et al.
Published: (2019-01-01)

An empirical Bayes model using a competition score for metabolite identification in gas chromatography mass spectrometry
by: Kim Seongho, et al.
Published: (2011-10-01)

The pitfall of the transient, inconsistent anticancer capacity of antiestrogens and the mechanism of apparent antiestrogen resistance
by: Suba Z
Published: (2015-08-01)

Increased expression of the HDAC9 gene is associated with antiestrogen resistance of breast cancers
by: Aurélien Linares, et al.
Published: (2019-07-01)

Autophagy and senescence facilitate the development of antiestrogen resistance in ER positive breast cancer
by: Michael K. McGrath, et al.
Published: (2024-03-01)

Breast cancer cells with acquired antiestrogen resistance are sensitized to cisplatin-induced cell death.
by: Yde, C, et al.
Published: (2007)

Aurora A and Mcl-1: new potential treatment targets in antiestrogen-resistant breast cancer
by: Christina W. Yde
Published: (2021-11-01)

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.
by: Maria Kalyuga, et al.
Published: (2012-01-01)

Exosome-Mediated Transfer of Cancer Cell Resistance to Antiestrogen Drugs
by: Svetlana E. Semina, et al.
Published: (2018-04-01)

Changes in Vascularization of Human Breast Cancer Xenografts Responding to Antiestrogen Therapy
by: Claus A. Kristensen, et al.
Published: (1999-12-01)

Response of estrogen receptor-positive breast cancer tumorspheres to antiestrogen treatments.
by: Ada Ao, et al.
Published: (2011-04-01)

Enhanced NFκB and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer
by: Moore Dan H, et al.
Published: (2007-04-01)

A Novel Metastatic Estrogen Receptor-Expressing Breast Cancer Model with Antiestrogen Responsiveness
by: Kendall L. Langsten, et al.
Published: (2023-12-01)

Estrogenic or antiestrogenic therapies for multiple myeloma?
by: Renoir Jack-Michel, et al.
Published: (2007-09-01)

Estrogen induces global reorganization of chromatin structure in human breast cancer cells.
by: Raphaël Mourad, et al.
Published: (2014-01-01)

Inhibition of Antiestrogen-Promoted Pro-Survival Autophagy and Tamoxifen Resistance in Breast Cancer through Vitamin D Receptor
by: Ye Li, et al.
Published: (2021-05-01)

Functional ablation of pRb activates Cdk2 and causes antiestrogen resistance in human breast cancer cells.
by: Hemant Varma, et al.
Published: (2007-12-01)

Reduced expression of miR-200 family members contributes to antiestrogen resistance in LY2 human breast cancer cells.
by: Tissa T Manavalan, et al.
Published: (2013-01-01)

Response of Symbiotic Endomycorrhizal Fungi to Estrogens and Antiestrogens
by: Marie-Josée Poulin, et al.
Published: (1997-05-01)

Antiestrogenic Activity of the Xi-Huang Formula for Breast Cancer by Targeting the Estrogen Receptor α
by: Jian Hao, et al.
Published: (2018-07-01)

The antiestrogenic effects of black cohosh on BRCA1 and steroid receptors in breast cancer cells
by: Crone M, et al.
Published: (2019-02-01)

HAS2-Ezrin-ER axis plays a role in acquired antiestrogen resistance of ER-positive breast cancer
by: Xiaodan Sun, et al.
Published: (2022-10-01)

SRC drives growth of antiestrogen resistant breast cancer cell lines and is a marker for reduced benefit of tamoxifen treatment.
by: Sarah L Larsen, et al.
Published: (2015-01-01)

Structural insights into the mode of action of a pure antiestrogen.
by: Pike, A, et al.
Published: (2001)

Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer
by: Kyung-min Lee, et al.
Published: (2020-10-01)

A Closer Look at Estrogen Receptor Mutations in Breast Cancer and Their Implications for Estrogen and Antiestrogen Responses
by: Léa Clusan, et al.
Published: (2021-01-01)

The influence of cis-regulatory elements on DNA methylation fidelity.
by: Mingxiang Teng, et al.
Published: (2012-01-01)

Breast cancer antiestrogen resistance 3 (BCAR3) promotes cell motility by regulating actin cytoskeletal and adhesion remodeling in invasive breast cancer cells.
by: Ashley L Wilson, et al.
Published: (2013-01-01)

Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity in Antiestrogen-Resistant Breast Cancer Cells.
by: Yu Mi Woo, et al.
Published: (2015-01-01)

Model-based peak alignment of metabolomic profiling from comprehensive two-dimensional gas chromatography mass spectrometry
by: Jeong Jaesik, et al.
Published: (2012-02-01)

Protein Aggregation Patterns Inform about Breast Cancer Response to Antiestrogens and Reveal the RNA Ligase RTCB as Mediator of Acquired Tamoxifen Resistance
by: Inês Direito, et al.
Published: (2021-06-01)

G0S2 promotes antiestrogenic and pro-migratory responses in ER+ and ER- breast cancer cells
by: Andrea K. Corbet, et al.
Published: (2023-07-01)

Estrogen receptor-alpha 36 mediates mitogenic antiestrogen signaling in ER-negative breast cancer cells.
by: XinTian Zhang, et al.
Published: (2012-01-01)

Curcumin Induces Cell Death and Restores Tamoxifen Sensitivity in the Antiestrogen-Resistant Breast Cancer Cell Lines MCF-7/LCC2 and MCF-7/LCC9
by: Min Jiang, et al.
Published: (2013-01-01)

Gingival cell growth with antiresorptive treatment combined with corticosteroids or antiestrogen
by: Heidi M. Ekholm, et al.
Published: (2021-08-01)

EB1089 Increases the Antiproliferative Response of Lapatinib in Combination with Antiestrogens in HER2-Positive Breast Cancer Cells
by: Angèle Sorel Achounna, et al.
Published: (2024-03-01)

Design and Synthesis of Novel Breast Cancer Therapeutic Drug Candidates Based upon the Hydrophobic Feedback Approach of Antiestrogens
by: Kiminori Ohta, et al.
Published: (2019-11-01)

Study on the effect of aromatase inhibitors and antiestrogens on the sex differentiation of broiler chicks
by: E.A Valizadeh, et al.
Published: (2011-02-01)

Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer
by: Chung Jae, et al.
Published: (2009-06-01)

Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer.
by: Yang, J, et al.
Published: (2015)