Blocking P2Y2 purinergic receptor prevents the development of lipopolysaccharide-induced acute respiratory distress syndrome

Blocking P2Y2 purinergic receptor prevents the development of lipopolysaccharide-induced acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is associated with high morbidity and mortality resulting from a direct or indirect injury of the lung. It is characterized by a rapid alveolar injury, lung inflammation with neutrophil accumulation, elevated permeability of the microvascular-barrier leadin...

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Bibliographic Details
Main Authors: Zahra Kargarpour, Sanja Cicko, Thomas C. Köhler, Andreas Zech, Slagjana Stoshikj, Christina Bal, Andreas Renner, Marco Idzko, Ahmed El-Gazzar
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
lipopolysaccharide
acute respiratory distress syndrome
purinergic receptors
P2RY2
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1310098/full

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