Visual masking & schizophrenia
Visual masking is a frequently used tool in schizophrenia research. Visual masking has a very high sensitivity and specificity and masking paradigms have been proven to be endophenotypes. Whereas masking is a powerful technique to study schizophrenia, the underlying mechanisms are discussed controve...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2015-06-01
|
| Series: | Schizophrenia Research: Cognition |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2215001315000116 |
| _version_ | 1819126522021150720 |
|---|---|
| author | Michael H. Herzog Andreas Brand |
| author_facet | Michael H. Herzog Andreas Brand |
| author_sort | Michael H. Herzog |
| collection | DOAJ |
| description | Visual masking is a frequently used tool in schizophrenia research. Visual masking has a very high sensitivity and specificity and masking paradigms have been proven to be endophenotypes. Whereas masking is a powerful technique to study schizophrenia, the underlying mechanisms are discussed controversially. For example, for more than 25 years, masking deficits of schizophrenia patients were mainly attributed to a deficient magno-cellular system (M-system). Here, we show that there is very little evidence that masking deficits are magno-cellular deficits. We will discuss the magno-cellular and other approaches in detail and highlight their pros and cons. |
| first_indexed | 2024-12-22T07:57:22Z |
| format | Article |
| id | doaj.art-1ae5569a11f84c94bf9d33d60e655272 |
| institution | Directory Open Access Journal |
| issn | 2215-0013 |
| language | English |
| last_indexed | 2024-12-22T07:57:22Z |
| publishDate | 2015-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Schizophrenia Research: Cognition |
| spelling | doaj.art-1ae5569a11f84c94bf9d33d60e6552722022-12-21T18:33:20ZengElsevierSchizophrenia Research: Cognition2215-00132015-06-0122647110.1016/j.scog.2015.04.001Visual masking & schizophreniaMichael H. Herzog0Andreas Brand1Laboratory of Psychophysics, Brain Mind Institute, École Polytechnique Fédérale de Lausanne (EPFL), SwitzerlandKlinikum Bremen-Ost, Bremen, GermanyVisual masking is a frequently used tool in schizophrenia research. Visual masking has a very high sensitivity and specificity and masking paradigms have been proven to be endophenotypes. Whereas masking is a powerful technique to study schizophrenia, the underlying mechanisms are discussed controversially. For example, for more than 25 years, masking deficits of schizophrenia patients were mainly attributed to a deficient magno-cellular system (M-system). Here, we show that there is very little evidence that masking deficits are magno-cellular deficits. We will discuss the magno-cellular and other approaches in detail and highlight their pros and cons.http://www.sciencedirect.com/science/article/pii/S2215001315000116Hyperactive magno-cellular systemHypoactive magno-cellular systemEndophenotypesEarly visual processingSchizophrenia |
| spellingShingle | Michael H. Herzog Andreas Brand Visual masking & schizophrenia Schizophrenia Research: Cognition Hyperactive magno-cellular system Hypoactive magno-cellular system Endophenotypes Early visual processing Schizophrenia |
| title | Visual masking & schizophrenia |
| title_full | Visual masking & schizophrenia |
| title_fullStr | Visual masking & schizophrenia |
| title_full_unstemmed | Visual masking & schizophrenia |
| title_short | Visual masking & schizophrenia |
| title_sort | visual masking schizophrenia |
| topic | Hyperactive magno-cellular system Hypoactive magno-cellular system Endophenotypes Early visual processing Schizophrenia |
| url | http://www.sciencedirect.com/science/article/pii/S2215001315000116 |
| work_keys_str_mv | AT michaelhherzog visualmaskingschizophrenia AT andreasbrand visualmaskingschizophrenia |