Diagnosis and management of the infected total knee replacement: a practical surgical guide

Abstract Purpose Prosthetic joint infection (PJI) after total knee arthroplasty (TKA) is a significant burden in health care. Diagnosis and proper management are challenging. A standardised procedure for the diagnostic workup and surgical management provides clear benefits in outcome. Methods Severa...

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Main Authors: Akos Zahar, Martin Sarungi
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Journal of Experimental Orthopaedics
Subjects:
Online Access:https://doi.org/10.1186/s40634-021-00333-2
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author Akos Zahar
Martin Sarungi
author_facet Akos Zahar
Martin Sarungi
author_sort Akos Zahar
collection DOAJ
description Abstract Purpose Prosthetic joint infection (PJI) after total knee arthroplasty (TKA) is a significant burden in health care. Diagnosis and proper management are challenging. A standardised procedure for the diagnostic workup and surgical management provides clear benefits in outcome. Methods Several diagnostic protocols and definitions for PJI were established in recent years. Proper PJI diagnosis remains critical for success and for choosing the optimal treatment option. A distinct workup of diagnostic steps, the evaluation of the results in a multidisciplinary setup and the meticulous surgical management of the infection are the key factors of successful treatment. Results The management of PJI after TKA consists of early revision with debridement and implant retention (DAIR) in early cases or staged revision in late infections beyond 30 days postoperative or after onset of acute symptoms. The revision is performed as a two‐stage procedure with the use of a fixed or mobile antibiotic spacer, or in selected cases as a single‐stage operation with the use of local and systemic antibiotic treatment. Conclusions This paper reflects the opinion of two revision surgeons who follow the same protocol for diagnosis and treatment of PJI after TKA, highlighting the key steps in diagnosis and management. Level of evidence Expert’s opinion
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spelling doaj.art-1ae6cbaca0a942b89ad3fda55f02e3dc2024-02-07T15:16:41ZengWileyJournal of Experimental Orthopaedics2197-11532021-01-0181n/an/a10.1186/s40634-021-00333-2Diagnosis and management of the infected total knee replacement: a practical surgical guideAkos Zahar0Martin Sarungi1Department of Orthopaedic & Trauma SurgeryHelios Klinikum Emil von BehringWalterhöferstrasse 1114165BerlinGermanyOrthopaedic DepartmentThe Golden Jubilee National HospitalGlasgowScotland, UKAbstract Purpose Prosthetic joint infection (PJI) after total knee arthroplasty (TKA) is a significant burden in health care. Diagnosis and proper management are challenging. A standardised procedure for the diagnostic workup and surgical management provides clear benefits in outcome. Methods Several diagnostic protocols and definitions for PJI were established in recent years. Proper PJI diagnosis remains critical for success and for choosing the optimal treatment option. A distinct workup of diagnostic steps, the evaluation of the results in a multidisciplinary setup and the meticulous surgical management of the infection are the key factors of successful treatment. Results The management of PJI after TKA consists of early revision with debridement and implant retention (DAIR) in early cases or staged revision in late infections beyond 30 days postoperative or after onset of acute symptoms. The revision is performed as a two‐stage procedure with the use of a fixed or mobile antibiotic spacer, or in selected cases as a single‐stage operation with the use of local and systemic antibiotic treatment. Conclusions This paper reflects the opinion of two revision surgeons who follow the same protocol for diagnosis and treatment of PJI after TKA, highlighting the key steps in diagnosis and management. Level of evidence Expert’s opinionhttps://doi.org/10.1186/s40634-021-00333-2Prosthetic joint infection (PJI)Total knee arthroplasty (TKA)Diagnostic protocolSurgical treatmentOne‐stage septic exchangeTwo‐stage revision
spellingShingle Akos Zahar
Martin Sarungi
Diagnosis and management of the infected total knee replacement: a practical surgical guide
Journal of Experimental Orthopaedics
Prosthetic joint infection (PJI)
Total knee arthroplasty (TKA)
Diagnostic protocol
Surgical treatment
One‐stage septic exchange
Two‐stage revision
title Diagnosis and management of the infected total knee replacement: a practical surgical guide
title_full Diagnosis and management of the infected total knee replacement: a practical surgical guide
title_fullStr Diagnosis and management of the infected total knee replacement: a practical surgical guide
title_full_unstemmed Diagnosis and management of the infected total knee replacement: a practical surgical guide
title_short Diagnosis and management of the infected total knee replacement: a practical surgical guide
title_sort diagnosis and management of the infected total knee replacement a practical surgical guide
topic Prosthetic joint infection (PJI)
Total knee arthroplasty (TKA)
Diagnostic protocol
Surgical treatment
One‐stage septic exchange
Two‐stage revision
url https://doi.org/10.1186/s40634-021-00333-2
work_keys_str_mv AT akoszahar diagnosisandmanagementoftheinfectedtotalkneereplacementapracticalsurgicalguide
AT martinsarungi diagnosisandmanagementoftheinfectedtotalkneereplacementapracticalsurgicalguide