Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury
Which contralesional circuits adapt after traumatic brain injury (TBI) is unclear. Here the authors used in vivo imaging, retrograde labeling, rabies tracing, clearing and functional imaging to demonstrate that callosal neurons selectively adapt after TBI in mice.
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-29992-0 |
| _version_ | 1811235396687757312 |
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| author | Laura Empl Alexandra Chovsepian Maryam Chahin Wing Yin Vanessa Kan Julie Fourneau Valérie Van Steenbergen Sanofer Weidinger Maite Marcantoni Alexander Ghanem Peter Bradley Karl Klaus Conzelmann Ruiyao Cai Alireza Ghasemigharagoz Ali Ertürk Ingrid Wagner Mario Kreutzfeldt Doron Merkler Sabine Liebscher Florence M. Bareyre |
| author_facet | Laura Empl Alexandra Chovsepian Maryam Chahin Wing Yin Vanessa Kan Julie Fourneau Valérie Van Steenbergen Sanofer Weidinger Maite Marcantoni Alexander Ghanem Peter Bradley Karl Klaus Conzelmann Ruiyao Cai Alireza Ghasemigharagoz Ali Ertürk Ingrid Wagner Mario Kreutzfeldt Doron Merkler Sabine Liebscher Florence M. Bareyre |
| author_sort | Laura Empl |
| collection | DOAJ |
| description | Which contralesional circuits adapt after traumatic brain injury (TBI) is unclear. Here the authors used in vivo imaging, retrograde labeling, rabies tracing, clearing and functional imaging to demonstrate that callosal neurons selectively adapt after TBI in mice. |
| first_indexed | 2024-04-12T11:51:16Z |
| format | Article |
| id | doaj.art-1ae8af63caf147c5851d208a6526975f |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-12T11:51:16Z |
| publishDate | 2022-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-1ae8af63caf147c5851d208a6526975f2022-12-22T03:34:10ZengNature PortfolioNature Communications2041-17232022-05-0113111610.1038/s41467-022-29992-0Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injuryLaura Empl0Alexandra Chovsepian1Maryam Chahin2Wing Yin Vanessa Kan3Julie Fourneau4Valérie Van Steenbergen5Sanofer Weidinger6Maite Marcantoni7Alexander Ghanem8Peter Bradley9Karl Klaus Conzelmann10Ruiyao Cai11Alireza Ghasemigharagoz12Ali Ertürk13Ingrid Wagner14Mario Kreutzfeldt15Doron Merkler16Sabine Liebscher17Florence M. Bareyre18Institute of Clinical Neuroimmunology, University Hospital, LMU MunichInstitute of Clinical Neuroimmunology, University Hospital, LMU MunichInstitute of Clinical Neuroimmunology, University Hospital, LMU MunichInstitute of Clinical Neuroimmunology, University Hospital, LMU MunichInstitute of Clinical Neuroimmunology, University Hospital, LMU MunichInstitute of Clinical Neuroimmunology, University Hospital, LMU MunichInstitute of Clinical Neuroimmunology, University Hospital, LMU MunichInstitute of Clinical Neuroimmunology, University Hospital, LMU MunichMax von Pettenkofer-Institute, Virology, Faculty of Medicine, & Gene Center, LMU MunichInstitute of Clinical Neuroimmunology, University Hospital, LMU MunichMax von Pettenkofer-Institute, Virology, Faculty of Medicine, & Gene Center, LMU MunichInstitute for Tissue Engineering and Regenerative Medicine (iTERM), Helmholtz Zentrum MünchenInstitute for Tissue Engineering and Regenerative Medicine (iTERM), Helmholtz Zentrum MünchenInstitute for Tissue Engineering and Regenerative Medicine (iTERM), Helmholtz Zentrum MünchenDepartment of Pathology and Immunology, Division of Clinical Pathology, CMU, University & University Hospitals of Geneva, Rue Michel-ServetDepartment of Pathology and Immunology, Division of Clinical Pathology, CMU, University & University Hospitals of Geneva, Rue Michel-ServetDepartment of Pathology and Immunology, Division of Clinical Pathology, CMU, University & University Hospitals of Geneva, Rue Michel-ServetInstitute of Clinical Neuroimmunology, University Hospital, LMU MunichInstitute of Clinical Neuroimmunology, University Hospital, LMU MunichWhich contralesional circuits adapt after traumatic brain injury (TBI) is unclear. Here the authors used in vivo imaging, retrograde labeling, rabies tracing, clearing and functional imaging to demonstrate that callosal neurons selectively adapt after TBI in mice.https://doi.org/10.1038/s41467-022-29992-0 |
| spellingShingle | Laura Empl Alexandra Chovsepian Maryam Chahin Wing Yin Vanessa Kan Julie Fourneau Valérie Van Steenbergen Sanofer Weidinger Maite Marcantoni Alexander Ghanem Peter Bradley Karl Klaus Conzelmann Ruiyao Cai Alireza Ghasemigharagoz Ali Ertürk Ingrid Wagner Mario Kreutzfeldt Doron Merkler Sabine Liebscher Florence M. Bareyre Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury Nature Communications |
| title | Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury |
| title_full | Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury |
| title_fullStr | Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury |
| title_full_unstemmed | Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury |
| title_short | Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury |
| title_sort | selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury |
| url | https://doi.org/10.1038/s41467-022-29992-0 |
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