Predictors of success in establishing orthotopic patient-derived xenograft models of triple negative breast cancer

Predictors of success in establishing orthotopic patient-derived xenograft models of triple negative breast cancer

Abstract Patient-derived xenograft (PDX) models of breast cancer are an effective discovery platform and tool for preclinical pharmacologic testing and biomarker identification. We established orthotopic PDX models of triple negative breast cancer (TNBC) from the primary breast tumors of patients pr...

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Dettagli Bibliografici
Autori principali: Gloria V. Echeverria, Shirong Cai, Yizheng Tu, Jiansu Shao, Emily Powell, Abena B. Redwood, Yan Jiang, Aaron McCoy, Amanda L. Rinkenbaugh, Rosanna Lau, Alexander J. Trevarton, Chunxiao Fu, Rebekah Gould, Elizabeth E. Ravenberg, Lei Huo, Rosalind Candelaria, Lumarie Santiago, Beatriz E. Adrada, Deanna L. Lane, Gaiane M. Rauch, Wei T. Yang, Jason B. White, Jeffrey T. Chang, Stacy L. Moulder, W. Fraser Symmans, Susan G. Hilsenbeck, Helen Piwnica-Worms
Natura: Articolo
Lingua:English
Pubblicazione: Nature Portfolio 2023-01-01
Serie:npj Breast Cancer
Accesso online:https://doi.org/10.1038/s41523-022-00502-1

Accesso online

https://doi.org/10.1038/s41523-022-00502-1

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