Phenotypic and Genetic Evolutions of a Porcine Reproductive and Respiratory Syndrome Modified Live Vaccine after Limited Passages in Pigs

Phenotypic and Genetic Evolutions of a Porcine Reproductive and Respiratory Syndrome Modified Live Vaccine after Limited Passages in Pigs

Modified live vaccines (MLVs) against the porcine reproductive and respiratory syndrome virus (PRRSV) have been regularly associated with safety issues, such as reversion to virulence. In order to characterize the phenotypic and genetic evolution of the PRRSV-1 DV strain from the Porcilis<sup>...

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Bibliographic Details
Main Authors: Julie Eclercy, Patricia Renson, Edouard Hirchaud, Mathieu Andraud, Véronique Beven, Frédéric Paboeuf, Nicolas Rose, Yannick Blanchard, Olivier Bourry
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Vaccines
Subjects:
PRRS virus
modified live vaccine
attenuation
variants
mutation
Online Access:https://www.mdpi.com/2076-393X/9/4/392

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