Upregulation of β-catenin signaling represents a single common pathway leading to the various phenotypes of spinal degeneration and pain
Abstract Spine degeneration is an aging-related disease, but its molecular mechanisms remain unknown, although elevated β-catenin signaling has been reported to be involved in intervertebral disc degeneration. Here, we determined the role of β-catenin signaling in spinal degeneration and in the home...
Main Authors: | Ke Lu, Qingyun Wang, Hua Jiang, Jun Li, Zhou Yao, Yongcan Huang, Jianquan Chen, Yejia Zhang, Guozhi Xiao, Xueyu Hu, Zhuojing Luo, Liu Yang, Liping Tong, Di Chen |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-04-01
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Series: | Bone Research |
Online Access: | https://doi.org/10.1038/s41413-023-00253-0 |
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