Preparation and In Vitro-In Vivo Evaluation of Luteolin Loaded Gastroretentive Microsponge for the Eradication of <i>Helicobacter pylori</i> Infections

Preparation and In Vitro-In Vivo Evaluation of Luteolin Loaded Gastroretentive Microsponge for the Eradication of <i>Helicobacter pylori</i> Infections

The current study aimed to develop a luteolin gastric floating microsponge for targeting <i>Helicobacter pylori</i>. The microsponge formulations were prepared by a quasi-emulsion method, and then evaluated for various physicochemical variables. The best microsponge was further assessed...

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Bibliographic Details
Main Authors: Mohammed Jafar, Mohammed Salahuddin, Mohd Sajjad Ahmad Khan, Yasir Alshehry, Nazar Radwan Alrwaili, Yazeed Ali Alzahrani, Syed Sarim Imam, Sultan Alshehri
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceutics
Subjects:
luteolin
buoyancy
<i>H. pylori</i>
microparticulate system
in vivo study
Online Access:https://www.mdpi.com/1999-4923/13/12/2094

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