Substantiation of a clopidogrel metabolism-associated gene (CYP2C19) variation among healthy individuals

Substantiation of a clopidogrel metabolism-associated gene (CYP2C19) variation among healthy individuals

Background: It is essential to investigate the prevalence of CYP2C19 alleles that affect drug metabolism. This study measures the allelic and genotypic frequencies of CYP2C19 loss-of-function (LoF) alleles CYP2C19∗2, CYP2C19∗3, and gain-of-function (GoF) alleles CYP2C19∗17 in the general population....

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Main Authors: Anshu Kumar Yadav, Aparna Kodakkat Chakkumkollath, Aysha Helna, Siddharth Birla, Rajesh Kumar Thimmulappa, Sunil Kumar Shambu, Prashant Vishwanath, Akila Prashant
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Indian Heart Journal
Subjects:
CYP2C19
Human
Adverse drug events
Pharmacogenomics
Clopidogrel
Online Access:http://www.sciencedirect.com/science/article/pii/S0019483223000883

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