Synthesis and spectroscopic analysis of Schiff Bases of Imesatin and Isatin derivatives
A series of new Schiff bases of Imesatin and Isatin derivatives which have been previously prepared from the reaction of Hydrazine monohydrate, p-phenylenediamine and 4,4- diaminodiphenylmethane with Isatin were reported. The compounds were characterized by elemental analyses, UV-visible, Infrared...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)
2016-11-01
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| Series: | Journal of Applied Sciences and Environmental Management |
| Subjects: | |
| Online Access: | https://www.ajol.info/index.php/jasem/article/view/147062 |
| Summary: | A series of new Schiff bases of Imesatin and Isatin derivatives which have been previously prepared from the reaction of Hydrazine monohydrate, p-phenylenediamine and 4,4- diaminodiphenylmethane with Isatin were reported. The compounds were characterized by elemental analyses, UV-visible, Infrared and Nuclear Magnetic Resonance (1H NMR and 13C NMR) spectroscopic analyses. The synthesized Schiff bases were obtained in moderate to excellent yields between 55.3 – 89.3%. Infrared spectra of all synthesized compounds contain the characteristic azomethine linkage (-CH=N) between 1580 – 1630 cm-1 and the N–H of the Isatin ring signals between δ 8.32 – 10.68 ppm in their 1H NMR spectra. The present work affords reaction pathway that is efficient and operational simplicity for the synthesis of Schiff bases derivatives.
Keywords: Schiff bases, isatin, imesatin, spectroscopic analysis, biological activity
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| ISSN: | 2659-1502 2659-1499 |