Electrothermal analysis of radiofrequency tissue ablation with injectable flexible electrodes considering bio-heat transfer
Flexible electrodes have been widely focused on in recent years due to their special mechanical properties, which can be directly integrated onto human soft tissues to actively take effects on human body or passively monitor human vital signs. These flexible electrodes provide a new routine to reali...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-05-01
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| Series: | Theoretical and Applied Mechanics Letters |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2095034921000659 |
| _version_ | 1819131059462209536 |
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| author | Min Hu Zhixiong Feng Yuguang Chu Yuhang Li |
| author_facet | Min Hu Zhixiong Feng Yuguang Chu Yuhang Li |
| author_sort | Min Hu |
| collection | DOAJ |
| description | Flexible electrodes have been widely focused on in recent years due to their special mechanical properties, which can be directly integrated onto human soft tissues to actively take effects on human body or passively monitor human vital signs. These flexible electrodes provide a new routine to realize clinical treatment of accurate thermal ablation in the biological tissues via radiofrequency ablation (RFA). Meanwhile, accurately controlling of thermal field is very significant for the thermal ablation in the clinical therapeutics to prevent the healthy tissue from excessive burning. In this paper, both one-dimensional and two-dimensional axisymmetric analytical models for the electrothermal analysis of radiofrequency ablation considering bio-heat transfer are established, which are verified by finite element analysis (FEA) and in vitro experiments on pig skins. In the model, the electrical field and thermal field are both derived analytically to accurately predict the temperature rise in the biological tissues. Furthermore, parameters, such as the blood flow convection in living tissues and thickness of tissue, have obvious effects on the thermal field in the tissues. They may pave the theoretical foundation and provide guidance of RFA with flexible electrodes in the future. |
| first_indexed | 2024-12-22T09:09:29Z |
| format | Article |
| id | doaj.art-1afb8ff665f14ea6a5dcc9121a2bd2da |
| institution | Directory Open Access Journal |
| issn | 2095-0349 |
| language | English |
| last_indexed | 2024-12-22T09:09:29Z |
| publishDate | 2021-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Theoretical and Applied Mechanics Letters |
| spelling | doaj.art-1afb8ff665f14ea6a5dcc9121a2bd2da2022-12-21T18:31:29ZengElsevierTheoretical and Applied Mechanics Letters2095-03492021-05-01114100258Electrothermal analysis of radiofrequency tissue ablation with injectable flexible electrodes considering bio-heat transferMin Hu0Zhixiong Feng1Yuguang Chu2Yuhang Li3Institute of Solid Mechanics, Beihang University (BUAA), Beijing 100191, ChinaPolice dog base of Beijing Public Security Bureau, Beijing 102614, ChinaDept Cardiovasc, China Academy of Chinese Medical Sciences Guang'anmen Hospital, Beijing 100053, ChinaInstitute of Solid Mechanics, Beihang University (BUAA), Beijing 100191, China; Corresponding author.Flexible electrodes have been widely focused on in recent years due to their special mechanical properties, which can be directly integrated onto human soft tissues to actively take effects on human body or passively monitor human vital signs. These flexible electrodes provide a new routine to realize clinical treatment of accurate thermal ablation in the biological tissues via radiofrequency ablation (RFA). Meanwhile, accurately controlling of thermal field is very significant for the thermal ablation in the clinical therapeutics to prevent the healthy tissue from excessive burning. In this paper, both one-dimensional and two-dimensional axisymmetric analytical models for the electrothermal analysis of radiofrequency ablation considering bio-heat transfer are established, which are verified by finite element analysis (FEA) and in vitro experiments on pig skins. In the model, the electrical field and thermal field are both derived analytically to accurately predict the temperature rise in the biological tissues. Furthermore, parameters, such as the blood flow convection in living tissues and thickness of tissue, have obvious effects on the thermal field in the tissues. They may pave the theoretical foundation and provide guidance of RFA with flexible electrodes in the future.http://www.sciencedirect.com/science/article/pii/S2095034921000659Flexible electrodsRadiofrequency ablationElectrothermal analysis |
| spellingShingle | Min Hu Zhixiong Feng Yuguang Chu Yuhang Li Electrothermal analysis of radiofrequency tissue ablation with injectable flexible electrodes considering bio-heat transfer Theoretical and Applied Mechanics Letters Flexible electrods Radiofrequency ablation Electrothermal analysis |
| title | Electrothermal analysis of radiofrequency tissue ablation with injectable flexible electrodes considering bio-heat transfer |
| title_full | Electrothermal analysis of radiofrequency tissue ablation with injectable flexible electrodes considering bio-heat transfer |
| title_fullStr | Electrothermal analysis of radiofrequency tissue ablation with injectable flexible electrodes considering bio-heat transfer |
| title_full_unstemmed | Electrothermal analysis of radiofrequency tissue ablation with injectable flexible electrodes considering bio-heat transfer |
| title_short | Electrothermal analysis of radiofrequency tissue ablation with injectable flexible electrodes considering bio-heat transfer |
| title_sort | electrothermal analysis of radiofrequency tissue ablation with injectable flexible electrodes considering bio heat transfer |
| topic | Flexible electrods Radiofrequency ablation Electrothermal analysis |
| url | http://www.sciencedirect.com/science/article/pii/S2095034921000659 |
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