Is Diet A Contributing Factor To Infertility?
Objective: To evaluate the effect of dietary trans-unsaturated fatty acids (TFAs) on ovulatory infertility in young unmarried females. Methods: This cross-sectional study was conducted from 1 august 2023 to 31 December 2023 at the Basic Medical Science Institute (BMSI), Jinnah Postgraduate Medical...
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| Format: | Article |
| Language: | English |
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KARACHI MEDICAL AND DENTAL COLLEGE
2024-02-01
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| Series: | Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College |
| Subjects: | |
| Online Access: | http://www.annals-ashkmdc.org/index.php/ashkmdc/article/view/753 |
| _version_ | 1827340565311651840 |
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| author | Ufaque Batool K Samo Kausar Abbas Saldera Rizwan Ali Lakho Gul Mohammad Kazi Maliha Shamim Sarah Hussain Sharif |
| author_facet | Ufaque Batool K Samo Kausar Abbas Saldera Rizwan Ali Lakho Gul Mohammad Kazi Maliha Shamim Sarah Hussain Sharif |
| author_sort | Ufaque Batool K Samo |
| collection | DOAJ |
| description |
Objective: To evaluate the effect of dietary trans-unsaturated fatty acids (TFAs) on ovulatory infertility in young unmarried females.
Methods: This cross-sectional study was conducted from 1 august 2023 to 31 December 2023 at the Basic Medical Science Institute (BMSI), Jinnah Postgraduate Medical Center Karachi. All healthy unmarried females aged 15-25 were included in the study. Females with a family history of infertility, having existing comorbidity, history of irregular menstruation cycle or hormonal replacement therapy, were excluded. Based on the Food frequency questionnaire score, 300 subjects were divided into 3 groups, Group A were low trans fats Consumers (Score 0-170), Group B was moderate trans fats consumers
(Score 171-340) and Group C were high trans fats consumers (Score 341-500). The analysis of results was carried out on SPSS Software version 22.
Results: The study’s 300 respondents, who ranged in age from 16 to 25, had a mean age of 21.8 years. Fifteen per cent of those in group “A” had abnormal HDL, 22% had bad LDL, and 23% had abnormal TGA, while 17% had abnormal cholesterol. An abnormal TGA, abnormal HDL, abnormal LDL, and abnormal 31% of the participants in group “B” exhibited abnormal cholesterol levels. A significant correlation between oxidative stress and hormonal indicators was found in three groups: “A” (13%) had aberrant LH, “20%” had abnormal FSH, “11%” had abnormal serum estrogen, “10%” had abnormal serum progesterone, and “C” (49% had abnormal LH, FSH, estrogen, and progesterone). Food frequency questionnaire (FFQ ) scores had a 25% positive correlation with cholesterol, a 40% negative correlation with HDL, a 31% positive correlation with LDL, and a 39% positive correlation with biochemical and hormonal indicators.
Conclusion: Trans fats diets significantly increase the risk of ovulatory infertility and reproductive failure in young females
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| first_indexed | 2024-03-07T21:21:39Z |
| format | Article |
| id | doaj.art-1afe8c092378459f9e6e70452b930625 |
| institution | Directory Open Access Journal |
| issn | 1563-3241 |
| language | English |
| last_indexed | 2024-03-07T21:21:39Z |
| publishDate | 2024-02-01 |
| publisher | KARACHI MEDICAL AND DENTAL COLLEGE |
| record_format | Article |
| series | Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College |
| spelling | doaj.art-1afe8c092378459f9e6e70452b9306252024-02-27T09:44:15ZengKARACHI MEDICAL AND DENTAL COLLEGEAnnals of Abbasi Shaheed Hospital and Karachi Medical & Dental College1563-32412024-02-01291Is Diet A Contributing Factor To Infertility?Ufaque Batool K Samo 0Kausar Abbas Saldera1Rizwan Ali Lakho2Gul Mohammad Kazi3Maliha Shamim4Sarah Hussain Sharif5Department of Physiology, Basic Medical Science Institute (BMSI), Jinnah Postgraduate Medical Center, KarachiDepartment of Physiology, Basic Medical Science Institute (BMSI), Jinnah Postgraduate Medical CenterDepartment of Urology, Sindh Institute of Urology and TransplantationDepartment of General Surgery, Jinnah Postgraduate Medical Center, Karachi Department of Physiology, Basic Medical Science Institute (BMSI), Jinnah Postgraduate Medical CenterDepartment of Internal Medicine, Central Government Dispensaries, Border Health Services-Pakistan. Objective: To evaluate the effect of dietary trans-unsaturated fatty acids (TFAs) on ovulatory infertility in young unmarried females. Methods: This cross-sectional study was conducted from 1 august 2023 to 31 December 2023 at the Basic Medical Science Institute (BMSI), Jinnah Postgraduate Medical Center Karachi. All healthy unmarried females aged 15-25 were included in the study. Females with a family history of infertility, having existing comorbidity, history of irregular menstruation cycle or hormonal replacement therapy, were excluded. Based on the Food frequency questionnaire score, 300 subjects were divided into 3 groups, Group A were low trans fats Consumers (Score 0-170), Group B was moderate trans fats consumers (Score 171-340) and Group C were high trans fats consumers (Score 341-500). The analysis of results was carried out on SPSS Software version 22. Results: The study’s 300 respondents, who ranged in age from 16 to 25, had a mean age of 21.8 years. Fifteen per cent of those in group “A” had abnormal HDL, 22% had bad LDL, and 23% had abnormal TGA, while 17% had abnormal cholesterol. An abnormal TGA, abnormal HDL, abnormal LDL, and abnormal 31% of the participants in group “B” exhibited abnormal cholesterol levels. A significant correlation between oxidative stress and hormonal indicators was found in three groups: “A” (13%) had aberrant LH, “20%” had abnormal FSH, “11%” had abnormal serum estrogen, “10%” had abnormal serum progesterone, and “C” (49% had abnormal LH, FSH, estrogen, and progesterone). Food frequency questionnaire (FFQ ) scores had a 25% positive correlation with cholesterol, a 40% negative correlation with HDL, a 31% positive correlation with LDL, and a 39% positive correlation with biochemical and hormonal indicators. Conclusion: Trans fats diets significantly increase the risk of ovulatory infertility and reproductive failure in young females http://www.annals-ashkmdc.org/index.php/ashkmdc/article/view/753DietUnhealthyTrans FatsLipidsInfertility |
| spellingShingle | Ufaque Batool K Samo Kausar Abbas Saldera Rizwan Ali Lakho Gul Mohammad Kazi Maliha Shamim Sarah Hussain Sharif Is Diet A Contributing Factor To Infertility? Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College Diet Unhealthy Trans Fats Lipids Infertility |
| title | Is Diet A Contributing Factor To Infertility? |
| title_full | Is Diet A Contributing Factor To Infertility? |
| title_fullStr | Is Diet A Contributing Factor To Infertility? |
| title_full_unstemmed | Is Diet A Contributing Factor To Infertility? |
| title_short | Is Diet A Contributing Factor To Infertility? |
| title_sort | is diet a contributing factor to infertility |
| topic | Diet Unhealthy Trans Fats Lipids Infertility |
| url | http://www.annals-ashkmdc.org/index.php/ashkmdc/article/view/753 |
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